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Your search keyword '"Pagani, Nicole"' showing total 2 results
Start Over Author "Pagani, Nicole" Topic drug dosage
2 results on '"Pagani, Nicole"'

1. Pharmacokinetics of caspofungin increased dosage in a patient on rifampin-containing anti-tubercular treatment.

Author

Calcagno, Andrea, Baietto, Lorena, Pagani, Nicole, Bertucci, Roberto, Rostagno, Roberto, D'Avolio, Antonio, Di Perri, Giovanni, and De Rosa, Francesco Giuseppe

Subjects
TUBERCULOSIS treatment, RIFAMPIN, DRUG dosage, ANTITUBERCULAR agents, PHARMACOKINETICS, GENETIC regulation
Abstract

We describe a patient treated with caspofungin and rifampin; after increasing the dosage of the former (70 mg/day) we observed an unexpectedly lower plasma exposure (AUC0-24 79.5 μg/ml*h vs. 108.8 μg/ml*h). Although rifampin-mediated complete enzyme induction may take longer than 2 weeks, the clinical advantage of an increased caspofungin dose deserves clinical investigation. [ABSTRACT FROM AUTHOR]

Published
2013
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2. Pharmacokinetics of high dosage of linezolid in two morbidly obese patients.

Author

Corcione, Silvia, Pagani, Nicole, Baietto, Lorena, Fanelli, Vito, Urbino, Rosario, Marco Ranieri, V., Di Perri, Giovanni, D'Avolio, Antonio, and De Rosa, Francesco G.

Subjects
*DRUG dosage, *LINEZOLID, *OVERWEIGHT persons, *HEALTH
Abstract

A letter to the editor is presented in response to the article about the risk of high dosage of linezolid in obese patients in the previous issue.

Published
2015
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