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Conventional fabrication of metal Nanoparticles results with a huge price tag and is hazardous to the environment. Hence "Green Technologies" is preferred. This work exhibits modest and bio-friendly fabrication methods of Manganese Oxide (MnO) nanoparticles (NPs) with Trigonella Foenum-Graecum (TFG) commonly known as Fenugreek. The extract prepared from fenugreek seeds acts as both reducing as well as capping agent. The work also exhibits an in-depth comparative study on the Hydrothermal method and Bio-reduction method of synthesis on MnO nanoparticles using fenugreek seeds. The structural and morphological characterizations have been done using SEM, X-Ray Diffraction, TEM and compound formation by FTIR, EDX. UV-Vis spectroscopy exhibits two different band gaps for two different methods of synthesis. The Drug release percentage of both the samples with different concentrations and pH were examined and calculated. The study demonstrates that Manganese Oxide nanoparticle formed from Fenugreek seeds by hydrothermal method and Bio-reduction method. [ABSTRACT FROM AUTHOR]

Ferrites have been serving as clinical elements over the past few years as contrasting agents in MRI, gene transfection, gene consignment and to attach cytotoxic drugs for targeted drug delivery. In this study, we report the synthesis of zinc ferrite and silver substituted zinc ferrite and its novel applications on drug delivery. The magnetic nanoparticle was characterised using XRD, SEM, TEM, UV-Vis spectroscopy, FT-IR and VSM. This magnetic particle was loaded with Curcumin, an anticancer drug coating with casein which plays a vital role as a natural polymer. The drug release studies were done under external and internal stimuli such as initial concentration of drug, magnetic fields and various pH, respectively. We have developed a pH-sensitive, higher drug concentration drug delivery system under 5 mT magnetic fields which is efficient for targeting drug delivery to the malignant cell. [ABSTRACT FROM AUTHOR]

A simple procedure of solvothermal synthesis of Silver doped Nickel ferrite nanoparticle is described in this paper for the application of drug delivery. The microwave absorption and SERS phenomena of silver nanoparticles and water-absorbent property of the polymer material such as polyethylene glycol (PEG) to bypass fast identification by the antibodies are made use in the synthesis of Ag-doped nickel ferrite with PEG as a solvent. The ferrite sample was distinguished using XRD, FTIR, SEM, TEM, and VSM. The absorption wavelength and corresponding band gap energy were calculated by UV-Vis spectroscopy. The drug delivery efficiency of silver doped nickel ferrite sample was conducted with curcumin by changing pH, initial drug concentration and specified magnetic field. Results prove that the addition of silver and polyethylene glycol in nickel ferrites changes the properties of the nanoparticle and recognised as a good material for drug delivery applications. [ABSTRACT FROM AUTHOR]