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Objective: To investigate the effects of GanHaiWeiKang capsule in treatment of chronic superficial gastritis. Methods: From March 2013 to March 2015 in our hospital gastroenterology. 128 chronic gastritis patients accorded were equally randomly divided into treatment group and control group. The patients in treatment group were given GanHaiWeiKang capsule and domperidone tablets treatment, and the patients in control group were given domperidone tablets, the two groups were treated for 4 weeks. Then the efficacy, traditional Chinese medical score and life quality score were observed. Results: The total effective rate in the treatment group and control group were 96.9 % and 84.4 % respectively that the total effective rate in the treatment group was significantly higher (P<0.05). The TCM scores in the treatment group and the control group were 2.19 ± 1.11 points and 5.09 ± 1.56 points after treatment that were significantly lower than before treatment of 17.34 ± 1.34 points and 17.39 ± 1.45 points (P<0.05) and had significant differences between groups (P<0.05). After treatment, the physiological function, physiological function, general health, vitality, social function, emotional function and mental health scores in the treatment group were significantly higher (P<0.05). Conclusions: GanHaiWeiKang capsule for treatment of chronic superficial gastritis can effectively relieve symptoms, improve curative efficacy and life equality, worthy of clinical application. [ABSTRACT FROM AUTHOR]