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We describe in this work the syntheses, characterization and antifungal activity of the complexes: [Ni{S 2 CNMe(R 1 )} 2 ] (1) , [Pd{S 2 CNMe(R 1 )} 2 ] (2) , [Pt{S 2 CNMe(R 1 )} 2 ] (3) , [Ni{S 2 CNMe(R 2 )} 2 ] (4) , [Pd{S 2 CNMe(R 2 )} 2 ] (5) , [Pt{S 2 CNMe(R 2 )} 2 ] (6) , {R 1 = CH 2 CH(OMe) 2 and R 2 = 2-methyl-1,3-dioxolane}. Complexes (1) – (6) have been characterized by IR and 1 H and 13 C NMR spectroscopy. In addition, the structures of (1) , (2) and (3) have been authenticated by X-ray diffraction. The antifungal activities of (1) – (6) have been screened against Aspergillus flavus , Aspergillus niger , Aspergillus parasiticus and Penicillium citrinum and the results, in the form of the minimum inhibition concentration (MIC), and compared with those of nystatin and miconazole nitrate, used as control drugs. All complexes had greater activity than nystatin. Palladium containing complexes, (2) and (5) , were the more active against A. flavus . The growth of A. niger , were more efficiently affected by Ni(II) complexes (1) and (4) and complex (6) was effective in reducing the colonies of A. parasiticus . [ABSTRACT FROM AUTHOR]

In this work, we describe the syntheses, characterization, and antifungal activity of [In{S2CNR(R1)}3] (1), [Ga{S2CNR(R1)}3] (2), [Bi{S2CNR(R1)}3] (3), [In{S2CNR(R2)}3] (4), [Ga{S2CNR(R2)}3] (5), and [Bi{S2CNR(R2)}3] (6) {R?=?Me; R1?=?CH2CH(OMe)2; and R2?=?2-methyl-1,3-dioxolane}. All complexes have been characterized using infrared and1H and13C spectroscopy, and the structures of1,3,4, and6have been authenticated by X-ray diffraction. The In(III)–dithiocarbamate bonding scheme depicts a distorted octahedral with asymmetric In(III)–S bonds and S–In–S angles. A pentagonal bipyramid is observed for the corresponding Bi(III) complexes with intermolecular Bi–S associations through the lone pair of electrons. The antifungal activities of1–6have been screened againstAspergillus niger,Aspergillus parasiticus, andPenicillium citrinum, and the results have been compared with those of nystatin and miconazole nitrate, as control drugs. [ABSTRACT FROM PUBLISHER]