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17 results on '"Sourkes TL"'

1. (18F) Fluoro-Dopa: a unique gamma emitting substrate for Dopa decarboxylase.

Author

Firnau G, Garnett ES, Sourkes TL, and Missala K

Subjects
Animals, Brain drug effects, Carbon Radioisotopes, Dihydroxyphenylalanine metabolism, Fluorine, Gamma Rays, Kidney drug effects, Kinetics, Methyldopa pharmacology, Pyridoxal Phosphate pharmacology, Rabbits, Radioisotopes, Swine, Brain metabolism, Dihydroxyphenylalanine analogs & derivatives, Dopa Decarboxylase metabolism, Kidney metabolism, Radionuclide Imaging methods
Published
1975
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8. On the mode of action of L-dopa in Parkinson's disease.

Author

Sourkes TL

Subjects
Brain metabolism, Catechols, Chemical Phenomena, Chemistry, Dihydroxyphenylalanine metabolism, Dopa Decarboxylase, Dopamine beta-Hydroxylase, Humans, Methyltransferases, Parkinson Disease enzymology, Parkinson Disease metabolism, Dihydroxyphenylalanine therapeutic use, Parkinson Disease drug therapy
Published
1970
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9. Central actions of dopa and dopamine.

Author

Sourkes TL

Subjects
Amphetamine pharmacology, Animals, Behavior, Animal drug effects, Brain drug effects, Cats, Corpus Striatum drug effects, Dihydroxyphenylalanine metabolism, Dogs, Dopamine biosynthesis, Dopamine metabolism, Dopamine Antagonists, Electroencephalography, Hypothalamo-Hypophyseal System drug effects, Methyltyrosines pharmacology, Mice, Monoamine Oxidase Inhibitors pharmacology, Motor Activity drug effects, Rabbits, Rats, Reserpine pharmacology, Substantia Nigra drug effects, Synapses drug effects, Tyrosine 3-Monooxygenase antagonists & inhibitors, Central Nervous System drug effects, Dihydroxyphenylalanine pharmacology, Dopamine pharmacology
Published
1972

10. Actions of levodopa and dopamine in the central nervous system.

Author

Sourkes TL

Subjects
Animals, Apomorphine pharmacology, Binding Sites, Brain drug effects, Chlorpromazine pharmacology, Dihydroxyphenylalanine therapeutic use, Dopamine physiology, Haplorhini, Hydrazines pharmacology, Methyltyrosines pharmacology, Parkinson Disease drug therapy, Rabbits, Rats, Receptors, Cholinergic, Receptors, Neurotransmitter, Reserpine pharmacology, Substantia Nigra, Synapses, Synaptic Transmission, Central Nervous System drug effects, Dihydroxyphenylalanine pharmacology, Dopamine pharmacology, Neurotransmitter Agents physiology
Published
1971

11. Possible new metabolites mediating actions of L-dopa.

Author

Sourkes TL

Subjects
Acetaldehyde, Animals, Aporphines, Brain metabolism, Catecholamines, Dihydroxyphenylalanine therapeutic use, Dopamine metabolism, Haplorhini, Humans, Isoquinolines, Parkinson Disease drug therapy, Plants metabolism, Dihydroxyphenylalanine metabolism
Published
1971
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12. A CLINICAL AND METABOLIC STUDY OF DOPA (3, 4-DIHYDROXYPHENYLALANINE) AND METHYLDOPA IN HUNTINGTON'S CHOREA.

Author

SOURKES TL, PIVNICKI D, BROWN WT, WISEMAN-DISTLER H, MURPHY GF, SANKOFF I, and SAINTCYR S

Subjects
Humans, Body Fluids, Chorea, Dihydroxyphenylalanine, Drug Therapy, Electroencephalography, Fluids and Secretions, Huntington Disease, Injections, Injections, Intravenous, Leriche Syndrome, Metabolism, Methyldopa, Parkinsonian Disorders, Urine
Published
1965
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15. Apomorphine, pimozide, L-Dopa and the probenecid test in Huntington's chorea.

Author

Lal S, De la Vega C, Garelis E, and Sourkes TL

Subjects
Clinical Trials as Topic, Evaluation Studies as Topic, Female, Homovanillic Acid cerebrospinal fluid, Humans, Huntington Disease cerebrospinal fluid, Huntington Disease diagnosis, Huntington Disease drug therapy, Hydroxyindoleacetic Acid cerebrospinal fluid, Male, Middle Aged, Placebos, Sensory Receptor Cells drug effects, Sensory Receptor Cells metabolism, Serotonin metabolism, Apomorphine therapeutic use, Dihydroxyphenylalanine therapeutic use, Dopamine metabolism, Huntington Disease metabolism, Pimozide therapeutic use, Probenecid
Published
1973

17. Metabolism of dihydroxyphenylalanine and tryptophan in pyridoxine-deficient rats.

Author

Sourkes TL and Missala K

Subjects
Animals, Brain Chemistry, Carbon Dioxide metabolism, Carbon Isotopes, Diet, Dihydroxyphenylalanine administration & dosage, Dihydroxyphenylalanine urine, Dopamine metabolism, Dopamine urine, Epinephrine analysis, Humans, Liver analysis, Male, Myocardium analysis, Norepinephrine analysis, Organ Size, Phenylacetates metabolism, Phenylacetates urine, Rats, Respiration, Spleen analysis, Dihydroxyphenylalanine metabolism, Tryptophan metabolism, Vitamin B 6 Deficiency metabolism
Published
1969
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