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Hidradenocarcinomas are very rare malignant sweat gland tumors that possess an infiltrative and/or low metastatic potential. Here we describe an interesting case of hidradenoma on the fronto-parietal region of the scalp of an elderly female, part of which had developed carcinomatous changes, infiltrating up to the pericranium. She developed intense itching, pain, spontaneous ulceration and rapid increase in the size of the tumor correlating with the expression of malignant behavior of the neoplasm. An initial incision biopsy suggested features of benign poroid hidradenoma, while the histology from the excised tumor exhibited a fairly well circumscribed epithelial neoplasm in dermis consisting of interconnected nodules as well as differentiated ducts, the neoplastic cells showing mild pleomorphism of nuclei, mitotic figures and abundant pale cytoplasm. Clefts, sclerotic stroma and foci of necrosis en mass were also seen. The final diagnosis was a well differentiated and slow growing hidradenocarcinoma. The tumor recurred locally despite total excision. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 56-year-old male presented with a painful and red left eye for 4 days, which was preceded by fever. It notes patient have history of pemphigus vulgaris (PV), which treated with oral prednisolone, azathioprine, and rituximab; and mentions presence of anterior scleritis in patient.

The article describes the case of a 60-year-old female presented with painful vesiculo-bullous lesion over right side chest and back. Case highlights include differential diagnosis of herpes zoster and lymphedema with lymphangioma and cutaneous metastasis, major sites of metastases in breast carcinoma, and skin biopsy showing mild atrophic epidermis with intraepidermal bulla and presence of atypical cells infiltrating into dermis.

The article discusses a case of a 50-year-old male on dialysis for renal failure with a gradually increasing, mildly painful, warty lesion on the left hand. Topics include a diagnosis of acroangiodermatitis associated with iatrogenic arteriovenous fistula mimiking verruca vulgaris, the cause of the lesions created by the arteriovenous fistula on the left forearm during dialysis, and the complete disappearance of the lesions when the patient was started on peritoneal dialysis.