Search

Your search keyword '"Hopwood ML"' showing total 7 results
Start Over Author "Hopwood ML" Topic diethylstilbestrol
7 results on '"Hopwood ML"'

6. Uptake of Diethylstilbestrol by Edible Plants

Author

Shimoda W, Cruea Dd, Hopwood Ml, and Hacker Rg

Subjects
Carbon Isotopes, Diethylstilbestrol, General Medicine, Biology, Soil, Botany, Genetics, Edible plants, medicine, Animals, Cattle, Animal Science and Zoology, Plants, Edible, Fertilizers, Food Science, medicine.drug
Published
1967

7. Conjugation of C-14-diethylstilbestrol by chicken liver in vitro

Author

F. X. Gassner, Hopwood Ml, and H. Karg

Subjects
Ethanol, Chromatography, Diethylstilbestrol, Ether, In Vitro Techniques, General Biochemistry, Genetics and Molecular Biology, In vitro, chemistry.chemical_compound, Paper chromatography, Hydrolysis, chemistry, Liver, Food, medicine, Animals, Incubation, Chickens, Physiological Phenomena, Conjugate, medicine.drug
Abstract

SummaryChicken liver was incubated with C14-labeled diethylstilbestrol (C14-DES). Without incubation 94.6% of the radioactivity was extracted with ethanol while after incubation only 82.6% was removed from the tissue. Partition of the radioactivity between water and ether at pH 7 gave 7% of the counts in water from unincubated tissue and 75% of the counts in water after incubation. Hydrolysis of the aqueous portion with β-glucuronidase and paper chromatography established that the material was conjugated DES. Assay of the extracts for uterotropic activity using immature mice indicated that the conjugate was but 8% as potent as the free compound although incubation caused a 50% loss of estrogenic potency.

Published
1963

Catalog

Books, media, physical & digital resources
See catalog results