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Background and Objectives: Diarrheal disease is the second important reason of death in children under 5 years old and is responsible for killing around 760,000 children every year. Diarrhea can last for several days and it can leave the body without the water and salts that are necessary for survival. Most people who die from diarrhea actually die from severe dehydration and fluid loss. The aim of this study is to assess the relationship between mother’s knowledge and their practice about diarrhea in children