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Results of the assessment of the economy sectors development as a whole and by regional distribution are presented in the article. Methods of analysis and synthesis, analytical generalizations, graphical and statistical, as well as mathematical modeling are used. The main trends of changes in the quantitative and qualitative indicators of assessment are identified. In terms of the share of profitable enterprises, the situation has a positive trend in the construction sector of the economy and is observed in large and medium-sized enterprises. In the segment of small business, the activity of enterprises of the assessed sectors of the economy is characterized by an increase in the share of unprofitable financial results of economic entities, due to the lack of opportunities to compete with large and medium-sized businesses. An increase in the service sector in 2020 was recorded due to the regrouping of development in the direction of increasing the possibility of conducting economic activity in intermediary spheres with a simultaneous decline in the priority of sectors that directly create the consumer product. It is proposed to diagnose the effectiveness of the economic entities functioning by factors, taking into account structural changes in the size of the business and their impact on the resulting indicator. The results of the assessment are presented, taking into account structural changes in the types of business by size, by quantitative indicators of assessment. The obtained assessment results make it possible to state the slowing down of the processes of economic development by quantitative factors of impact, taken into account in terms of the trend of changes that occurred in the period 2016-2020. The determined changes in the factor of priority of business choice by size are characterized by a declining trend of deviations in all its areas, but in small business there have been slight positive changes in the direction of increasing sales. [ABSTRACT FROM AUTHOR]