1. Low Glycemic Index Prototype Isomaltulose-Update of Clinical Trials.
- Author
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Maresch CC, Petry SF, Theis S, Bosy-Westphal A, and Linn T
- Subjects
- Athletic Performance, Body Weight Maintenance, Clinical Trials as Topic, Cognition, Diabetes Mellitus, Type 1 blood, Diabetes Mellitus, Type 2 blood, Diet, Reducing adverse effects, Female, Humans, Isomaltose adverse effects, Isomaltose therapeutic use, Male, Nutritive Sweeteners adverse effects, Overweight prevention & control, Pregnancy, Pregnancy Complications prevention & control, Sports Nutritional Physiological Phenomena, Weight Reduction Programs, Diabetes Mellitus, Type 1 diet therapy, Diabetes Mellitus, Type 2 diet therapy, Diet, Diabetic adverse effects, Glycemic Index, Hyperglycemia prevention & control, Isomaltose analogs & derivatives, Nutritive Sweeteners therapeutic use
- Abstract
Low glycemic index diets are supposed to achieve a more beneficial effect on blood glucose control in people with diabetes mellitus and may also provide metabolic benefits for the general population. A prototype of a low-glycemic index carbohydrate is the natural occurring disaccharide isomaltulose that can be commercially produced from sucrose (beet sugar) to industrial scale. It is currently used in various food and drink applications as well as special and clinical nutrition feeds and formula diet as a food ingredient and alternative sugar. Here we provide an overview on clinical trials with isomaltulose including an analysis of its effects on glycemia and fat oxidation as compared to high glycemic index sugars and carbohydrates. In addition, we discuss recent reports on beneficial effects in weight-loss maintenance and pregnancy.
- Published
- 2017
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