1. Putamen functional connectivity during inhibitory control in smokers and non-smokers
- Author
-
Akkermans, S.E., Luijten, M., Rooij, D. van, Franken, I.H.A., Buitelaar, J.K., Department of Psychology, Education and Child Studies, and Clinical Psychology
- Subjects
All institutes and research themes of the Radboud University Medical Center ,Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7] ,nervous system ,mental disorders ,Developmental Psychopathology ,150 000 MR Techniques in Brain Function ,psychological phenomena and processes - Abstract
Contains fulltext : 182022.pdf (Publisher’s version ) (Closed access) The putamen has been shown to play a key role in inhibitory control and addiction, and consists of distinct subregions associated with distinct functions. The anterior putamen is thought to be specialized in goal-directed control or response-monitoring in connection with frontal regions, whereas the posterior part is specialized in habitual or automatic responding in connection with sensorimotor regions. The present study is the first to delineate functional networks of the anterior and posterior putamen in a Go-NoGo response inhibition task, and to examine differences between smokers (n = 25) and non-smokers (n = 23) within these networks. Functional connectivity analyses were conducted on fMRI data from a Go-NoGo study, using the generalized form of psychophysiological interaction with anterior and posterior putamen seed regions. In the context of inhibition, the anterior putamen exhibited connectivity with the anterior cingulate cortex (ACC) and precuneus (pFWE
- Published
- 2018