1. Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe
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Chiara Cerami, Perminder S. Sachdev, Katrin Seeher, Nicole Kustyniuk, Paul K. Crane, Sandra Weintraub, Manfred Berres, Giovanni B. Frisoni, Ingo Kilimann, Alessandra Dodich, Clarissa Ferrari, Walter A. Kukull, Martina Pigliautile, Bruno Dubois, Mira Didic, David P. Salmon, Leonardo Sacco, Cristina Festari, Liesbeth Aerts, Stefan Klöppel, Emiliano Albanese, Nicola Girtler, Nicola Ballhausen, Andreas U. Monsch, Patrizia Mecocci, Alessio Toraldo, Fabricio Ferreira de Oliveira, Alice Grazia, Inez H.G.B. Ramakers, Jean-Marie Annoni, Flavio Nobili, EwXjLab caQTbQe, Kwun Chuen Gary Chan, Valentina Nicolosi, Bengt Winblad, Christian Chicherio, Michael Wagner, Suzie Diener, Jean Georges, Nicole A. Kochan, Stefano F. Cappa, Henry Brodaty, Daniel Ferreira, Eric Westman, Matthias Kliegel, Stefan J. Teipel, Daniele Altomare, Steven D. Shirk, Nathalie Mella, Andrea Brioschi-Guevara, Jean-François Démonet, Marina Boccardi, Isabelle Bos, Oliver Peters, Pieter Jelle Visser, Anton F. Gietl, Andreas Buchmann, Virginie Descloux, Lutz Froelich, Institut de Neurosciences des Systèmes (INS), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Developmental Psychology, Neurology, and Amsterdam Neuroscience - Neurodegeneration
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050103 clinical psychology ,Epidemiology ,diagnosis ,Consensus Development Conferences as Topic ,standard neuropsychological assessment ,Datasets as Topic ,Disease ,Neuropsychological Tests ,Alzheimer&apos ,cognitive assessment ,0302 clinical medicine ,Cognition ,MONTE-CARLO ,BEHAVIORAL VARIANT ,Neuropsychological assessment ,SELECTIVE REMINDING TEST ,Cognitive impairment ,610 Medicine & health ,ComputingMilieux_MISCELLANEOUS ,Language ,medicine.diagnostic_test ,Health Policy ,05 social sciences ,Age Factors ,standards [Neuropsychological Tests] ,Alzheimer's disease ,Europe ,ALZHEIMERS-DISEASE ,Psychiatry and Mental health ,classification [Cognitive Dysfunction] ,Educational Status ,DIFFERENTIAL-DIAGNOSIS ,Psychology ,Alzheimer’s disease ,Frontotemporal dementia ,Clinical psychology ,standards [Datasets as Topic] ,CONSENSUS STATEMENT ,Harmonization ,Article ,s disease ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,Sex Factors ,mild cognitive impairment ,Developmental Neuroscience ,AMNESTIC SYNDROME ,medicine ,Humans ,0501 psychology and cognitive sciences ,Cognitive Dysfunction ,ddc:610 ,mild neurocognitive disorders ,DATA SET UDS ,Expert Testimony ,[SCCO.NEUR]Cognitive science/Neuroscience ,medicine.disease ,COGNITIVE IMPAIRMENT ,diagnosis [Cognitive Dysfunction] ,Sample size determination ,SAMPLE-SIZE ,Normative ,Neurology (clinical) ,Geriatrics and Gerontology ,Neurocognitive ,030217 neurology & neurosurgery - Abstract
Introduction: Harmonized neuropsychological assessment for neurocognitive disorders, an international priority for valid and reliable diagnostic procedures, has been achieved only in specific countries or research contexts.Methods: To harmonize the assessment of mild cognitive impairment in Europe, a workshop (Geneva, May 2018) convened stakeholders, methodologists, academic, and non-academic clinicians and experts from European, US, and Australian harmonization initiatives.Results: With formal presentations and thematic working-groups we defined a standard battery consistent with the U.S. Uniform DataSet, version 3, and homogeneous methodology to obtain consistent normative data across tests and languages. Adaptations consist of including two tests specific to typical Alzheimer's disease and behavioral variant frontotemporal dementia. The methodology for harmonized normative data includes consensus definition of cognitively normal controls, classification of confounding factors (age, sex, and education), and calculation of minimum sample sizes.Discussion: This expert consensus allows harmonizing the diagnosis of neurocognitive disorders across European countries and possibly beyond.
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- 2022
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