1. Preliminary characterization of a CdZnTe photon detector for BNCT-SPECT
- Author
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Nicola Zambelli, Ian Postuma, Saverio Altieri, Andrea Zappettini, Nicoletta Protti, S. Fatemi, Silva Bortolussi, G. Benassi, M. Zanichelli, and Manuele Bettelli
- Subjects
Nuclear and High Energy Physics ,Photon ,Physics::Instrumentation and Detectors ,Physics::Medical Physics ,Single-photon emission computed tomography ,01 natural sciences ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Optics ,0103 physical sciences ,medicine ,Irradiation ,Energy resolution ,Instrumentation ,Physics ,Detector efficiency ,Range (particle radiation) ,medicine.diagnostic_test ,010308 nuclear & particles physics ,business.industry ,Detector ,Resolution (electron density) ,Semiconductor detector ,Neutron capture ,SPECT ,BNCT ,CdZnTe ,business - Abstract
The effectiveness of Boron Neutron Capture Therapy (BNCT) treatment depends on the amount of radiation dose deposited locally by the reaction 10B ( n , α ) 7 Li in the tumour; however, the local and real time measurement of this quantity during the neutron irradiation is a big challenge. To evaluate the dose it is necessary to know the spatial distribution of the 10 B concentration and thermal neutron flux in the tissue during the irradiation. One technique to solve this problem relies on the on-line detection of the 478 keV 7 Li de-excitation photons that can be used to map the spatial distribution of the reaction rate of the 10B ( n , α ) 7 Li. The present work has been developed within a project aiming to develop a Single Photon Emission Computed Tomography (SPECT) system based on CdZnTe (CZT) semiconductor detector. This work studied the performances of a 5 × 5 × 20 mm 3 CZT prototype detector focusing on the energy resolution and detection efficiency inside the energy range 200–1400 keV. The energy resolution at 478 keV is ∼ 3% and the detection efficiency is around 6%. These preliminary results confirms the feasibility of a CZT detector as a sensitive unit for a BNCT-SPECT imaging system.
- Published
- 2018
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