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Hyperesthesia (from the Greek hyper - increase and aisthesis - sensation) means any increase in pain sensitivity of the tooth tissues to external irritants of temperature, chemical and tactile nature. The number of the patients with hypersensitivity of the hard dental tissues has increased sharply in recent years and according to various authors’ findings it is from 60% to 90%. A wide range of prevalence fluctuations is observed in different age groups. The age of people with certain symptoms of teeth hypersensitivity is 25-50 years while the highest frequency is among the people aged 30-40 years. Starting from an earlier age women suffer more often than men. The generalized form of hyperesthesia is usually associated with such general causes as the functional state of the nervous system, endocrine diseases, disorders of mineral metabolism in the body. The localized forms of hyperesthesia are caused mainly by the defects in the hard tissues of individual teeth or periodontium. Rapid and effective treatment of hyperesthesia of the hard dental tissues is an important and urgent problem of modern practical dentistry. Therefore, a great amount of the techniques for the treatment of this pathology is constantly increasing. Now one of the most common methods is the local impact on the hard dental tissues. The aim of the study is to analyze the specialized medical literature that is concerned with modern methods and techniques for the treatment of hypersensitivity of the hard dental tissues. Materials and methods of the research. The review of the literature sources on modern concepts of the treatment of hyperesthesia of the hard dental tissues has been made and the information has been analyzed. Results. The problem of hypersensitivity of the tooth tissues has led to the invention of a whole class of the drugs aimed at its elimination. These medications have different chemical nature, the mechanism of the action on the tissues and even the indications for their use, but the purpose of all these medical preparations is common as they are aimed at reducing hypersensitivity of the tooth tissues. A wide range of the techniques is proposed to eliminate the problem of tooth sensitivity. One of the most common methods of the treatment is a local effect on the hard dental tissues which is aimed directly at the relief of the hydrodynamic mechanism. According to this theory, the stimulus which causes pain increases the flow of the fluid in the dentinal tubules that leads to the changes in osmotic pressure and increased activity of the nerve endings in its turn. Therefore, taking into account the mechanism of the action of desensitizing toothpastes they are divided into those ones that reduce the excitability of the nerve fiber and those ones that contribute to the obstruction of the dentinal tubules. Nowadays there have been also accumulated a sufficient number of clinical and experimental observations indicating that one of the main causes of dentin hypersensitivity is any disturbance of phosphorus-calcium metabolism of the hard dental tissues. A number of authors have shown that people with the generalized form of hyperesthesia has pronounced hypophosphatemia which is combined with the decrease in the content of inorganic phosphorus and calcium in the oral fluid. In this regard, the drugs of calcium (gluconate, chloride, glycerophosphate) and fluoride (sodium fluoride) are widespread in the treatment of dentin hyperesthesia and they are used by application and rubbing into sensitive areas, electro- and phonophoresis, in the form of varnishes and gels, as well as in toothpastes. Unfortunately, the mechanisms of dentinal pain have not been fully studied and its symptoms are nonspecific and subjective. Therefore, there is no ideal composition for the treatment of sensitive dentin. In addition, the result of the therapy occurs in many cases over a long period of time. Conclusion. Thus, according to modern ideas, the treatment of hypersensitivity of the hard dental tissues can be carried out in two ways: desensitization of the nerve fibers to reduce the corresponding response to irritation; obturation of the dentinal tubules to restore intra-tubular osmotic pressure. These days one hundred percent result in the treatment has not been achieved, so it is important to find and develop new techniques and methods to eliminate teeth hyperesthesia.

Harmonious facial aesthetics, proper bite, straight teeth are an integral part of individual psychological well-being and a modern person’s professional success. According to scientific studies, orthodontic pathology occupies third place in terms of incidence among dental diseases after dental caries and periodontal diseases. Being man-made polluted, the Donetsk region also has a high prevalence of dentoalveolar anomalies. In 7-15 year old children, the incidence rate is 68-90%. The aim of the study is to research the prevalence and structure of dentoalveolar anomalies among students of a medical university in the Donetsk region. Materials and methods. To fulfill the purpose of the study we analyzed the orthodontic status of 300 Donetsk National Medical University students. Examinations of students were performed according to the generally accepted method in dentistry. The material of the clinical trial was subjected to variational-statistical analysis in accordance with the purpose of the study. Results. The analysis of the study data showed that there were abnormalities in the attachment of the oral soft tissues, namely 56,0% (168/300) of those examined had a short bridle of the tongue, 20,0% (60/300) of students – a short bridle of the upper lip, 5,3% (16/300) patients – a short frenulum of the lower lip and 17,3% (52/300) of those examined – a shallow vestibule of the mouth. The data on the orthodontic status of the examined patients showed that the prevalence of dental anomalies was 98,7% (296/300). 64% (192/300) of examined subjects had anomalies of occlusion in combination with anomalies of individual teeth. Anomalies of individual teeth without occlusion pathology were diagnosed in 34,7% (104/300) of patients. 1,3% (4/300) of students have been found to be orthodontically healthy. Moreover, the case history of those examined shows that 30,7% (92/300) of students underwent orthodontic treatment in the past, which was not always successful. The external examination revealed facial signs of dentoalveolar anomalies in 50,0% (148/296) of students, which indicates the gnathic nature of orthodontic pathology. Deep bite (54,2%) and deep occlusion in combination with distal occlusion (25,0%) were significant. Class 2 pathology was detected in 10,4% (20/192) of individuals. The examination did not reveal any cases of open bite in the subjects. The prevalence of crossbite and mesial occlusion was low and amounted to 8,3% (16/192) and 2,1% (4/192) of cases, respectively. Teeth rotation was prevalent (71,6%; 212/296) among 296 students who had anomalies of individual teeth and dentition (isolated or combined with an occlusion anomaly). The results of the study indicate that 56,6% of those examined (120/212) had lower teeth rotation, 26,4% of subjects (56/212) presented with the combination of this pathology in both jaws, and tortoanomaly of upper teeth was found in 17,0% (36/212) of cases. Crowding of the frontal mandible segment was also a common pathology (58,1%;172/296), the first degree of this pathology’s severity being prevalent (79,0%; 136/172). Examination of students showed that 51,4% of subjects had a vestibular position of individual teeth (152/296). Oral position of teeth and crowding of the frontal upper segment were less common and were observed in 43,2% (128/296) and 29,7% (88/296) cases, respectively. Among the examined students diastemata and tremata were diagnosed in 13,5% (40/296) and 25,7% (76/296) cases, respectively. It should be noted that this pathology predominantly affected the upper jaw: diastema occured in 90% (36/40), and tremata in 57,9% (44/76) of cases. The examination revealed an abnormal inclination of the students’ front teeth. The overall prevalence of protrusion of incisors was 13,5% (40/296), maxillary protrusion of teeth being most prevalent (90%; 36/40). The incidence of incisor retrusion was 10,8% (32/296). Also, this pathology predominated in the upper jaw (87,5%; 28/32). The study of dentition disorders revealed the prevalence of transversely and sagittally oriented changes in the shape of dental arches. The results revealed that the shortening of the dentition was the most common dentition deformation, being detected in 66,9% (198/296) of cases. The narrowing of the dentition was found in 51,0% of subjects (151/296). Conclusions. Such studies allow to improve the prevention principles of dentoalveolar anomalies and to organize the timely provision of specialized medical care.