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This case report focuses on the rising incidence of oral and maxillofacial tumors, requiring multimodal therapy involving surgery and radiotherapy. Radiotherapy, integral to cancer treatment, poses oral health challenges, notably radiation-related caries. Severe complications such as mucositis, xerostomia, and osteoradionecrosis highlight the critical role of optimal oral hygiene practices in managing these conditions. The presented case involves a 38-year-old male with a history of verrucous carcinoma, undergoing composite resection, modified neck dissection, and pectoralis major myocutaneous flap reconstruction. Adjuvant radiotherapy requires a comprehensive approach to minimize complications. Here, the focus is on fluoride treatment, specifically Fluoritop SR Dental Varnish, to prevent radiation-related caries. A multidisciplinary approach, including fluoride application, vigilant monitoring, patient education, and collaboration, is crucial for minimizing complications in oral malignancy radiotherapy. Emphasizing fluoride’s significance in preventing radiation-related caries, this care plan contributes to awareness and improves oral health outcomes in this patient population.

Purpose: The purpose of this study was to analyze the incidence of various complications following routine exodontia performed using fixed protocols. Materials and Methods: A total of 22,330 extractions carried out in 14,975 patients, aged between 14 and 82 years, who reported to the Department of Oral and Maxillofacial Surgery at Padmashree Dr. D. Y. Patil Dental College and Hospital, Nerul, Navi Mumbai, were evaluated for various complications. Results: The most common complications encountered were tooth fracture, trismus, fracture of cortical plates and dry socket. Wound dehiscence, postoperative pain and hemorrhage were encountered less frequently. Luxation of adjacent teeth, fracture of maxillary tuberosity, and displacement of tooth into adjacent tissue spaces were rare complications. Conclusion: The practice of exodontia inevitably results in complications from time to time. It is imperative for the clinician to recognize impending complications and manage them accordingly.