1. Evaluation of a novel primer containing isocyanate group on dentin bonding durability.
- Author
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Yang ZY, Gao J, Duan LY, Luo ML, Yu F, Xu RC, Zhou MD, Tay FR, Niu LN, Zhou W, and Chen JH
- Subjects
- Dentin-Bonding Agents chemistry, Resin Cements chemistry, Dentin chemistry, Surface Properties, Methacrylates chemistry, Urethane, Uridine Monophosphate analysis, Tensile Strength, Materials Testing, Microscopy, Electron, Scanning, Dental Cements, Dental Bonding
- Abstract
Objectives: To evaluate the benefits of a novel dentin-bonding primer, namely, isocyanate-terminated urethane methacrylate precursor (UMP), which can form covalent bonds with demineralized dentin collagen., Methods: The synthesized and purified UMP monomer was characterized and tested its effects on the degree of conversion (DC) and wettability of an acetone-based dental adhesive. Then UMP primers of different concentrations were formulated and used to prepare adhesive specimens, which were compared with solvent-treated groups. Primer-treated specimens with and without aging were also compared. To evaluate the bonding interface, microtensile strength tests, nano-indentation tests and nanoleakage- eavaluation were performed using a field-emission scanning electron microscope and nano-indenter. Data were analyzed using SPSS 20.0 software with significance set at α = 0.05 using one-way analysis of variance (ANOVA) and two-way ANOVA to characterize the effects of the primer., Results: Treatment with the UMP primer promoted the DC and wettability of the adhesive on the demineralized dentin surface (P < 0.05); it also increased the bond strength of the aged dentin bonding interface (P < 0.05). Nanoleakage was reduced; the bonding interface became more stable, and the continuity and strength of the hybrid layer improved (P < 0.05) following UMP treatment. The application of 5 mM UMP as a primer for dentin bonding could lead to a stable bonding interface and long-lasting bonding effects., Significance: The use of 5 mM UMP primer developed in this study could improve dentin bonding durability and has excellent clinical application prospects., (Copyright © 2023 The Academy of Dental Materials. All rights reserved.)
- Published
- 2023
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