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Start Over Descriptor "Addenbrooke" Topic dementia
3 results on '"Addenbrooke"'

1. Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level

Author

José Wagner Leonel Tavares Júnior, Pedro Braga Neto, Janine de Carvalho Bonfadini, Lays Bittencourt, Candida Helena Lopes, Larissa Mendes, José Ibiapina Siqueira Neto, Valéria Sousa, Anina Amaral, Carolina Gomes Carrilho, Jonatan Oliveira Espindola, Maria Eduarda Avancini Casali, André Barciela Veras, and Gilberto Sousa Alves

Subjects
Dementia, cognitive screening, illiterate, Northeast, Addenbrooke, accuracy, Psychiatry, RC435-571
Abstract

ABSTRACT Objective: To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination Revised (ACE-R) as a cognitive screening tool for older adults with low levels of schooling and healthy aging, MCI and dementia in Brazil. Methods: All participants underwent neurological and psychiatric examinations and were administered a validated version of ACE-R. Results: A total of 85 participants were evaluated; most were females (84.7%, n = 72). The post hoc analysis showed statistical differences in ACE-R total scores between older adults with mild cognitive impairment (MCI) and controls (p < 0.001) and in subitem scores including verbal fluency, language, visuospatial skills and attention (p < 0.001). The visual-spatial skills subitem was the most strongly correlated with schooling level (r = 0.509, p < 0.001), whereas late, immediate recall and recognition memory were not influenced by schooling. The ACE-R had the best diagnostic accuracy in discriminating between MCI and controls = 0.69 (

Published
2021
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2. Características clínicas e acurácia do Exame Cognitivo Addenbrooke Versão revisada (ACE-R) em idosos com baixa escolaridade

Author

José Ibiapina Siqueira Neto, Janine de Carvalho Bonfadini, André Barciela Veras, Candida Helena Lopes, Carolina Gomes Carrilho, Anina Amaral, Pedro Braga Neto, Gilberto Alves, Maria Eduarda Avancini Casali, Jonatan Oliveira Espindola, Lays Bittencourt, Valéria Sousa, José Wagner Leonel Tavares Júnior, and Larissa Mendes

Subjects
cognitive screening, RC435-571, Diagnostic accuracy, Escolaridade, 03 medical and health sciences, 0302 clinical medicine, Post-hoc analysis, medicine, Dementia, Verbal fluency test, 030212 general & internal medicine, Aged, Recognition memory, Psychiatry, acurácia, accuracy, business.industry, Idoso, illiterate, Addenbrooke, Northeast, triagem cognitiva, Cognition, medicine.disease, Psychiatry and Mental health, analfabetos, Cognitive screening, Educational Status, Cognitive Assessment System, business, 030217 neurology & neurosurgery, Demência, Clinical psychology
Abstract

Objective: To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination Revised (ACE-R) as a cognitive screening tool for older adults with low levels of schooling and healthy aging, MCI and dementia in Brazil. Methods: All participants underwent neurological and psychiatric examinations and were administered a validated version of ACE-R. Results: A total of 85 participants were evaluated; most were females (84.7%, n = 72). The post hoc analysis showed statistical differences in ACE-R total scores between older adults with mild cognitive impairment (MCI) and controls (p < 0.001) and in subitem scores including verbal fluency, language, visuospatial skills and attention (p < 0.001). The visual-spatial skills subitem was the most strongly correlated with schooling level (r = 0.509, p < 0.001), whereas late, immediate recall and recognition memory were not influenced by schooling. The ACE-R had the best diagnostic accuracy in discriminating between MCI and controls = 0.69 (

Published
2021

3. Validation of Addenbrooke's cognitive examination for detecting early dementia in a Japanese population

Author

Yoshida, Hidenori, Terada, Seishi, Honda, Hajime, Ata, Toshie, Takeda, Naoya, Kishimoto, Yuki, Oshima, Etsuko, Ishihara, Takeshi, and Kuroda, Shigetoshi

Subjects
*DEMENTIA, *MINI-Mental State Examination, *POINT-of-care testing, *COGNITIVE analysis, *COMPARISON (Psychology), *FRONTOTEMPORAL dementia, *PHYSICIAN practice patterns, *JAPANESE people
Abstract

Abstract: There is a clear need for brief, but sensitive and specific, cognitive screening instruments for dementia. We assessed the diagnostic accuracy of the Japanese version of Addenbrooke''s Cognitive Examination (ACE) in identifying early dementia in comparison with the conventional Mini-Mental State Examination (MMSE). Standard tests for evaluating dementia screening tests were applied. A total of 201 subjects (Alzheimer''s disease (AD)=65, frontotemporal dementia (FTD)=24, vascular dementia=26, dementia with Lewy bodies=11, mild cognitive impairment (MCI)=13, and controls=62) participated in this study. The reliability of the ACE was very good (alpha coefficient=0.82). In our patient series, the sensitivity for diagnosing dementia with an ACE score of ≤74 was 0.889 with a specificity of 0.987, and the sensitivity of an ACE score of ≤80 was 0.984 with a specificity of 0.867. The Japanese version of the ACE is a very accurate instrument for the detection of early dementia, and should be widely used in clinical practice. [Copyright &y& Elsevier]

Published
2011
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