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Accurately diagnosing sleep disorders is essential for clinical assessments and treatments. Polysomnography (PSG) has long been used for detection of various sleep disorders. In this research, electrocardiography (ECG) and electromayography (EMG) have been used for recognition of breathing and movement-related sleep disorders. Bio-signal processing has been performed by extracting EMG features exploiting entropy and statistical moments, in addition to developing an iterative pulse peak detection algorithm using synchrosqueezed wavelet transform (SSWT) for reliable extraction of heart rate and breathing-related features from ECG. A deep learning framework has been designed to incorporate EMG and ECG features. The framework has been used to classify four groups: healthy subjects, patients with obstructive sleep apnea (OSA), patients with restless leg syndrome (RLS) and patients with both OSA and RLS. The proposed deep learning framework produced a mean accuracy of 72% and weighted F1 score of 0.57 across subjects for our formulated four-class problem.

In an attempt to reduce the infection rate of the COrona VIrus Disease-19 (Covid-19) countries around the world have echoed the exigency for an economical, accessible, point-of-need diagnostic test to identify Covid-19 carriers so that they (individuals who test positive) can be advised to self isolate rather than the entire community. Availability of a quick turn-around time diagnostic test would essentially mean that life, in general, can return to normality-at-large. In this regards, studies concurrent in time with ours have investigated different respiratory sounds, including cough, to recognise potential Covid-19 carriers. However, these studies lack clinical control and rely on Internet users confirming their test results in a web questionnaire (crowdsourcing) thus rendering their analysis inadequate. We seek to evaluate the detection performance of a primary screening tool of Covid-19 solely based on the cough sound from 8,380 clinically validated samples with laboratory molecular-test (2,339 Covid-19 positive and 6,041 Covid-19 negative) under quantitative RT-PCR (qRT-PCR) from certified laboratories. All collected samples were clinically labelled, i.e., Covid-19 positive or negative, according to the results in addition to the disease severity based on the qRT-PCR threshold cycle (Ct) and lymphocytes count from the patients. Our proposed generic method is an algorithm based on Empirical Mode Decomposition (EMD) for cough sound detection with subsequent classification based on a tensor of audio sonographs and deep artificial neural network classifier with convolutional layers called ‘DeepCough’. Two different versions of DeepCough based on the number of tensor dimensions, i.e., DeepCough2D and DeepCough3D, have been investigated. These methods have been deployed in a multi-platform prototype web-app ‘CoughDetect’. Covid-19 recognition results rates achieved a promising AUC (Area Under Curve) of $98.80\% \pm 0.83\%$ 98. 80 % ± 0. 83 % , sensitivity of $96.43\% \pm 1.85\%$ 96. 43 % ± 1. 85 % , and specificity of $96.20\% \pm 1.74\%$ 96. 20 % ± 1. 74 % and average AUC of $81.08\% \pm 5.05\%$ 81. 08 % ± 5. 05 % for the recognition of three severity levels. Our proposed web tool as a point-of-need primary diagnostic test for Covid-19 facilitates the rapid detection of the infection. We believe it has the potential to significantly hamper the Covid-19 pandemic across the world. [ABSTRACT FROM AUTHOR]

The monitoring of physical activities and recognition of motion disorders belong to important diagnostical tools in neurology and rehabilitation. The goal of the present paper is in the contribution to this topic by (1) analysis of accelerometric signals recorded by wearable sensors located at specific body positions and by (2) implementation of deep learning methods to classify signal features. This paper uses the general methodology to analysis of accelerometric signals acquired during cycling at different routes followed by the global positioning system. The experimental dataset includes 850 observations that were recorded by a mobile device in the spine area (L3 verterbra) for cycling routes with the different slope. The proposed methodology includes the use of deep learning convolutional neural networks with five layers applied to signal values transformed into the frequency domain without specification of any signal features. The accuracy of discrimination between different motion patterns for the uphill and downhill cycling and recognition of 4 classes associated with different route slopes was 96.6% with the loss criterion of 0.275 for sigmoidal activation functions. These results were compared with those evaluated for selected sets of features estimated for each observation and classified by the support vector machine, Bayesian methods, and the two-layer neural network. The best cross-validation error of 0.361 was achieved for the two-layer neural network model with the sigmoidal and softmax transfer functions. Our methodology suggests that deep learning neural networks are efficient in the assessment of motion activities for automated data processing and have a wide range of applications, including rehabilitation, early diagnosis of neurological problems, and possible use in engineering as well. [ABSTRACT FROM AUTHOR]