1. Chronic neurobrucellosis due to Brucella melitensis.
- Author
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Bucher A, Gaustad P, and Pape E
- Subjects
- Adult, Agglutination immunology, Brucellosis cerebrospinal fluid, Brucellosis drug therapy, Deafness cerebrospinal fluid, Humans, Male, Paraplegia cerebrospinal fluid, Rifampin therapeutic use, Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use, Turkey ethnology, Brucellosis complications, Deafness etiology, Paraplegia etiology
- Abstract
A 20-year-old male Turkish immigrant to Norway suffering from severe chronic neurobrucellosis with spastic paraplegia and deafness is presented. The diagnosis was established by isolation of Brucella melitensis from cerebrospinal fluid (CSF) culture. Brucella antibody agglutination titers were high in serum and CSF. In spite of intensive, prolonged treatment with a combination of trimethoprim-sulfamethoxazole (TPM-SMZ), rifampicin and doxycycline, the course of the illness was characterized by relapses and severe neurological defects.
- Published
- 1990
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