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The Beidou Navigation Satellite Demonstration System and Beidou Regional Satellite Navigation System are accomplished, and the Beidou Global Satellite Navigation System (BDS-3) is under construction. Nineteen networking satellites have been launched by the end of November 2018. To assess the new and old signals of new networking satellites, the data quality is analyzed from the observation noise and pseudo-range multipath two aspects based on the data of iGMAS stations from 18th to 28th May 2018. The accuracies of BDS-3/GPS combined orbit determinations with B1I/B3I and B1C/B2a are compared. The results show that the data quality of the new signal B2a is similar to that of B1I/B3I, and the data quality of B1C is slightly worse than that of B1I/B3I. Comparing the orbit and clock correction accuracies of overlapped arcs (48 hours), the results with B1C/B2a are slightly better than those with B1I/B3I. The averaged 3D position accuracies (3D RMSs) of precise orbit determinations with B1C/B2a and B1I/B3I are around 35 cm. The RMS values of clock corrections are less than 0.5 ns. [ABSTRACT FROM AUTHOR]

Magnolol, a constituent of the bark of Magnolia officinalis, has been reported to decrease myocardial stunning and infarct size. In this study, we investigated whether magnolol can reduce renal ischemia and reperfusion (I/R) injury. Renal I/R, induced by a 60-min occlusion of bilateral renal arteries and a 24-h reperfusion, significantly increased blood urea nitrogen (BUN) and creatinine levels, and caused histological damage to the kidneys of rats. Apoptosis, as evaluated by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) staining and caspase-3 activation, was significantly increased in the kidneys. Furthermore, serum levels of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6) were significantly elevated, while the interleukin-10 (IL-10) level was suppressed. However, intravenous pretreatment with magnolol at doses of 0.003 mg/kg and 0.006 mg/kg 10 min before renal I/R significantly limited the increases of BUN, creatinine, the histological damage, and apoptosis in the kidneys. The increases in TNF-α, IL-1β, and IL-6, and the decrease in IL-10 were also significantly inhibited. Additionally, magnolol increased Bcl-2 and decreased Bax in the kidneys. Phosphorylation of the prosurvival kinases, including Akt and extracellular signal-regulated kinases 1 and 2 (ERK1/ 2), was elevated, while phosphorylation of the pro-apoptotic mitogen-activated protein kinases, including p38 and c-Jun N-terminal kinase (JNK), was suppressed. In conclusion, magnolol reduces renal I/R injury. The underlying mechanisms for this effect might be related to the prevention of apoptosis, possibly via the inhibition of both extrinsic and intrinsic apoptotic pathways, including the reduction of TNF-α production and the modulation of pro- and anti-apoptotic signaling elements. [ABSTRACT FROM AUTHOR]

Currently, interpretation of health examination reports relies primarily on the physician's own experience. If health screening data could be integrated with outpatient medical records to uncover correlations between disease and abnormal test results, the physician could benefit from having additional reference resources for medical examination report interpretation and clinic diagnosis. This study used the medical database of a regional hospital in Taiwan to illustrate how association rules can be found between abnormal health examination results and outpatient illnesses. The rules can help to build up a disease-prevention knowledge database that assists healthcare providers in follow-up treatment and prevention. Furthermore, this study proposes a new algorithm, the data cutting and sorting method, or DCSM, in place of the traditional Apriori algorithm. DCSM significantly improves the mining performance of Apriori by reducing the time to scan health examination and outpatient medical records, both of which are databases of immense sizes. [ABSTRACT FROM AUTHOR]

In this paper we introduced a kind of real-time image matching navigation algorithm based on ORB which can meet the requirement for high speed aircraft. We combined image matching with INS to fix the accumulative error of INS and get high accuracy position data of the aircraft. In order to improve the accuracy and robust of system, we used SIFT feature as a supplement of ORB and introduced the Kalman filter to optimize the output of image matching and INS. Based on maneuverability law, we did wrong point deleting with RANSAC. Finally, we designed a software system to simulate the image matching/INS navigation system. From the result of experiments, we can draw a conclusion that the algorithm has good real-time performance, play a good matching effect and get high accuracy position value. [ABSTRACT FROM AUTHOR]