1. A randomized trial of the effects of an almond-enriched, hypocaloric diet in the treatment of obesity.
- Author
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Foster, Gary D., Leh Shantz, Kerri., Vander Veur, Stephanie S., Oliver, Tracy L., Lent, Michelle R., Virus, Amy, Szapary, Philippe O., Rader, Daniel J., Zemel, Babette S., and Gilden-Tsai, Adam
- Subjects
REDUCING diets ,ALMOND ,ANALYSIS of variance ,ANTHROPOMETRY ,BLOOD pressure ,REGULATION of body weight ,CARDIOVASCULAR diseases risk factors ,CHI-squared test ,DIET in disease ,DIET therapy ,LIPIDS ,RESEARCH funding ,STATISTICS ,T-test (Statistics) ,X-ray densitometry in medicine ,DATA analysis ,BODY mass index ,RANDOMIZED controlled trials ,DATA analysis software - Abstract
Background: Increased consumption of nuts has been advocated because of their health benefits, but the role of nuts in the treatment of obesity is unclear given their high energy density. Objective: This study was designed to evaluate the effects of a hypocaloric, almond-enriched diet (AED) compared with a hypocaloric nut-free diet (NFD) on body weight and cardiovascular disease risk factors in the context of an 18-mo behavioral weight-management program. Design: Overweight and obese individuals [n = 123; age = 46.8 y, BMI (in kg/m
2 ) = 34.0] were randomly assigned to consume an AED or NFD and instructed in traditional behavioral methods of weight control. Anthropometric and metabolic measurements were made at baseline, 6 mo, and 18 mo. Results: Those in the AED group lost slightly but significantly less weight than did those in the NFD group at 6 mo (-5.5 compared with -7.4 kg; P = 0.04), but there were no differences at 18 mo. No significant differences in body composition were found between the groups at 6 or 18 mo. The AED, compared with the NFD, was associated with greater reductions in total cholesterol (P = 0.03), total:HDL cholesterol (p = 0.02), and triglycerides (P = 0.048) at 6 mo, and no differences were observed between the groups at 18 mo. Conclusions: The AED and NFD groups experienced clinically significant and comparable weight loss at 18 mo. Despite smaller weight loss in the AED group at 6 mo, the AED group experienced greater improvements in lipid profiles. This trial was registered at clinical- trials.gov as NCT00I94428. [ABSTRACT FROM AUTHOR]- Published
- 2012
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