1. Two new compounds from Melodinus suaveolens
- Author
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Bao Kun Zhu, Qian Xu Yang, Tian Dong Zhang, Meng Wang, Xi Feng Teng, and Jun Ling
- Subjects
Magnetic Resonance Spectroscopy ,010405 organic chemistry ,Stereochemistry ,Organic Chemistry ,Plant Science ,Biology ,Melodinus suaveolens ,010402 general chemistry ,biology.organism_classification ,Antineoplastic Agents, Phytogenic ,01 natural sciences ,Biochemistry ,digestive system diseases ,0104 chemical sciences ,Analytical Chemistry ,Apocynaceae ,Plant Leaves ,HeLa ,Cell Line, Tumor ,Cancer cell ,Humans ,Cytotoxic T cell ,Cytotoxicity - Abstract
Two new compounds, 19-hydroxy-melodinine K (1) and melodiside (2), and 25 known compounds were isolated from leaves and twigs of Melodinus suaveolens. Their structures were elucidated based on 1- and 2-D NMR, FTIR, UV and MS spectroscopic data. 19-hydroxy-melodinine K showed cytotoxic activity against MDA-MB-231 breast, BCG-823 gastric, SW480 colon and Hela cancer cells.
- Published
- 2016
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