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The research is devoted to studying the role of hygiene violations of an oral cavity and unsatisfactory denture care in formation of pathological process in the impression area. In total 178 patients with the diagnosis "tooth alignment stomatitis" who are constantly using removable dentures are examined. By means of a cytological method it is established that at clinical symptoms of tooth alignment stomatitis in cytogram of prints the Increase in dystrophic changes in flat epithelium cells was noted, layers of half-ruined lymphoid elements are noted, the number of microxyphil and mononuclear neutrophils under review sharply Magnifications to 60-70. It is established that the cytological method allows assessing the hygienic condition of an oral cavity in the impression area rather precisely that has important diagnostic value for defining tactics of holding treatment-and-prophylactic actions in case of tooth alignments stomatitis. [ABSTRACT FROM AUTHOR]