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Your search keyword '"Kao, Mark"' showing total 2 results
Start Over Author "Kao, Mark" Topic cyclodextrins
2 results on '"Kao, Mark"'

1. Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease.

Author

Vite, Charles H., Bagel, Jessica H., Swain, Gary P., Prociuk, Maria, Sikora, Tracey U., Stein, Veronika M., O’Donnell, Patricia, Ruane, Therese, Ward, Sarah, Crooks, Alexandra, Su Li, Mauldin, Elizabeth, Stellar, Susan, De Meulder, Marc, Kao, Mark L., Ory, Daniel S., Davidson, Cristin, Vanier, Marie T., and Walkley, Steven U.

Subjects
CYCLODEXTRINS, NIEMANN-Pick diseases, DRUG administration, CEREBELLUM diseases, PURKINJE cells, CELL death, SPHINGOLIPIDS, THERAPEUTICS
Abstract

The article focuses on a research on prevention of cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease by intracisternal cyclodextrin. Topics discussed include hepatic disease and progressive neurological disease due to increase in unesterified cholesterol and several sphingolipids; subcutaneous administration 2-hydroxypropyl-b-cyclodextrin (HPbCD) to cats; and efficacy and safety of drug administration directly into the central nervous system.

Published
2015
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2. Intracisternal cyclodextrin ameliorates neurological dysfunction, increases survival time, and stops Purkinje cell death in feline Niemann–Pick type C1 disease.

Author

Vite, Charles H., Bagel, Jessica H., Swain, Gary P., Prociuk, Maria, Sikora, Tracey U., O'Donnell, Patricia, Ruane, Therese, Ward, Sarah, Crooks, Alexandra, Li, Su, Mauldin, Elizabeth, Stein, Veronika, Ory, Daniel S., Kao, Mark L., Davidson, Cristin, Vanier, Marie T., and Walkely, Steven U.

Subjects
*PURKINJE cells, *CYCLODEXTRINS, *CELL death, *NIEMANN-Pick diseases, *NEUROLOGICAL disorders
Published
2015
Full Text
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