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Your search keyword '"Meo, Paolo Lo"' showing total 2 results
Start Over Author "Meo, Paolo Lo" Topic cyclodextrin
2 results on '"Meo, Paolo Lo"'

1. Cyclodextrin-Calixarene Nanosponges as Potential Platforms for pH-Dependent Delivery of Tetracycline.

Author

Fontana, Rosa Maria, Milano, Nicola, Barbara, Lorenzo, Di Vincenzo, Antonella, Gallo, Giuseppe, and Meo, Paolo Lo

Subjects
TETRACYCLINE, DRUG delivery systems, CARBOXYL group, CLINICAL drug trials
Abstract

Four mixed cyclodextrin-calixarene nanosponges were tested as possible Drug Delivery Systems, using Tetracycline antibiotic as a suitable model drug. The selected nanosponges featured a different composition ratio between the two host co-monomer components, and the possible presence of ionisable amine or carboxyl groups deriving from chemical post-modification. The pH-dependent absorption and release abilities of the materials were verified; in particular release kinetics showed the occurrence of a simple first-order profile. The antibacterial activity of nanosponge-tetracycline composites suitably prepared under sterile conditions was assayed towards both Gram-positive and Gram-negative typical bacterial strains, showing in some cases an interesting improvement of the biocidal activity. [ABSTRACT FROM AUTHOR]

Published
2019
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2. Evaluation of adsorption ability of Cyclodextrin-Calixarene Nanosponges towards Pb2+ ion in aqueous solution

Author

Paolo Lo Meo, Demetrio Milea, Alberto Pettignano, Antonella Di Vincenzo, Salvatore Cataldo, Pellegrino Conte, Cataldo, Salvatore, Meo, Paolo Lo, Conte, Pellegrino, Vincenzo, Antonella Di, Milea, Demetrio, and Pettignano, Alberto

Subjects
Nanosponges, Polymers and Plastics, Environmental remediation, Speciation, Inorganic chemistry, Remediation, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Ion, Metal, Adsorption, Calixarene, Materials Chemistry, Settore CHIM/01 - Chimica Analitica, chemistry.chemical_classification, Aqueous solution, Cyclodextrin, Organic Chemistry, Settore CHIM/06 - Chimica Organica, 021001 nanoscience & nanotechnology, FFC-NMR relaxometry, Lead, 0104 chemical sciences, Anodic stripping voltammetry, chemistry, visual_art, visual_art.visual_art_medium, 0210 nano-technology
Abstract

Different cyclodextrin-calixarene nanosponges (CyCaNSs) have been characterized by means of FFC-NMR relaxometry, and used as sorbents to remove Pb2+ ions from aqueous solutions. Considering that the removal treatments may involve polluted waters with different characteristics, the adsorption experiments were performed on solutions without and with the addition of background salts, under different operational conditions. The adsorption abilities and affinities of the nanosponges towards Pb2+ ions were investigated by measuring the metal ion concentration by means of Inductively Coupled Plasma Emission Spectroscopy (ICP-OES) and Differential Pulse Anodic Stripping Voltammetry (DP-ASV). The acid-base properties of nanosponges and of metal ion as well as their interactions with the other interacting components of the systems have been considered in the evaluation of adsorption mechanism. Recycling and reuse experiments on the most efficient adsorbents were also performed. On the grounds of the results obtained, post-modified CyCaNSs appear promising materials for designing environmental remediation devices.

Published
2021

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