Search

Introdaction:Leishmaniasis is a zoonosis disease, presented in three forms including cutaneous, mucocutaneous, and visceral (kala-azar). The parasite, Leishmania spp, is transferred by the causative agent of the disease, namely the sand-fly. Accurate identification of sand-flies helps to prevent and treat the disease. Materials and Methods:This study was conducted to identify sand-fly species distributed in Birjand, east of Iran. Sand-flies were collected from different parts of Birjand city, Iran through using sticky traps in summer 2015. Captured female specimens were mounted and identified by specific keys. Result:In this study, a total of 1480 samples of sand-flies were collected, out of which 945 sand-flies in areas were related to animal and 535 sand-flies in areas related to human. The most prevalent species, among 654 collected female specimens were Phlebotomus sergenti (22.17%) and Sergentomyia dentata (49.54%). Conclusion:According to the current results, the dominant species among disease vectors of cutaneous leishmaniasis is the urban type. Because of the presence of Leishmania tropica, the city's health system must take necessary care to control cutaneous leishmaniasis. [ABSTRACT FROM AUTHOR]

Background: Cutaneous leishmaniasis (CL) is one of the most important neglected tropical diseases and a major public health challenge in Iran caused by Leishmania spp and transmitted by phlebotomine sand flies. The number of CL cases has shown an increasing pattern all over the country, including the district of Varamin, southeast of Tehran, Iran. This study aimed to identify the Leishmania spp isolated from CL patients using molecular methods in Varamin during 2012-2013. Methods: Exudate materials collected from the swollen edge of the skin lesions of 44 parasitological positive CL patients by disposable lancet. They were referred to Varamin Health Center by physician. The samples were subjected to molecular method for Leishmania species identification. Results: The digestion pattern of restriction enzyme revealed that 37 (84.1%) CL patients were infected with L. major and 7 (15.9%) were infected with L. tropica. They were mostly male than female. More than half of the patients (58%) had multiple lesions, and they were mostly observed on extremities, 34.1% on legs and 29.5% on hands. Le- sions were mostly of wet ulcerative type. Conclusion: Dominancy of L. major provides more evidence that Varamin District probably could be considered as Zoonotic Cutaneous Leishmaniasis (ZCL) areas. More investigation on other epidemiological aspects of disease is needed. [ABSTRACT FROM AUTHOR]

Background and Objectives: Leishmaniasis is one of the most important diseases in Iran, with high prevalence in some part of country including, Tehran province. This study was aimed to investigate the cutaneous lesions of patients studies was also referred to different laboratory of Health center of Varamin (a city in Tehran province), sand flies species in selected area. Material and Methods: In this cross sectional study demographic data was collected by special questionnaire. Smears of suspected patients to stained and examined by microscope. Sand flies were collected by sticky traps, CDC light traps and aspirators, female specimens were mounted and identified by diagnostic keys at species level. Results: Leishmania parasites were observed in 56.82% of cases. Disease was more common among male (64%). The majority of patients (30%) aged between 25-39 year old. Most lesions (50%) observed in hands and legs of patients, 76% of affected people had just one lesion. Half of them had a history of travel to endemic areas. More than 2500 sand flies captured during this study; among them 1100 female specimens were mounted and identified. The prevalent spicies was Sergentomyia spp (65/9%), the second was. papatasi (33/20%). It should be mentioned that Ph. sergenti, Ph. alexandri and Ph. caucasicus group also were identified in lower percentage. Conclusion: According to current results and the status of the studied region including it seems that (Agricultural activities, animal husbandry and migration), cutaneous leishmaniasis could be a health threatening problem. [ABSTRACT FROM AUTHOR]