1. Antitumor Effects of Curcumin on Cervical Cancer with the Focus on Molecular Mechanisms: An Exegesis.
- Author
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Govahi A, Zahmatkesh N, Pourbagherian O, Khas NM, Salamzadeh T, Mehr HM, Babaei E, and Hajivalili M
- Subjects
- Female, Humans, Plant Extracts pharmacology, Antioxidants, Curcuma, Curcumin pharmacology, Curcumin therapeutic use, Uterine Cervical Neoplasms drug therapy
- Abstract
Cervical cancer is one of the most prevalent malignancies among females and is correlated with a significant fatality rate. Chemotherapy is the most common treatment for cervical cancer; however, it has a low success rate due to significant side effects and the incidence of chemo-resistance. Curcumin, a polyphenolic natural compound derived from turmeric, acts as an antioxidant by diffusing across cell membranes into the endoplasmic reticulum, mitochondria, and nucleus, where it performs its effects. As a result, it's been promoted as a chemo-preventive, anti-metastatic, and anti-angiogenic agent. As a consequence, the main goal of the present review was to gather research information that looked at the link between curcumin and its derivatives against cervical cancer., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
- Published
- 2023
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