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Your search keyword '"J.-F. Chabot"' showing total 3 results
Start Over Author "J.-F. Chabot" Topic culture techniques
3 results on '"J.-F. Chabot"'

1. Singularity of oncogenic activity of strain MC29 avian leukosis viruses

Author

D, Beard, J F, Chabot, A J, Langlois, E A, Hillman, and J W, Beard

Subjects
Microscopy, Electron, Blood Cells, Avian Leukosis, Avian Leukosis Virus, Liver, Staining and Labeling, Culture Techniques, Hematopoietic System, Animals, Chick Embryo, Peritoneum, Kidney, Pericardium
Published
1970

2. Component of Strain MC29 Avian Leukosis Virus with the Property of Defectiveness

Author

R. Ishizaki, J. F. Chabot, A. J. Langlois, and J. W. Beard

Subjects
animal structures, viruses, Immunology, Fluorescent Antibody Technique, Chick Embryo, Virus Replication, Microbiology, Avian sarcoma virus, Quail, Defective virus, Virus, Cell Line, Neutralization Tests, Virology, Culture Techniques, Animal Viruses, Viral Interference, Animals, Microscopy, Phase-Contrast, Antigens, Viral, Rous sarcoma virus, biology, Avian Leukosis Virus, Staining and Labeling, Complement Fixation Tests, Defective Viruses, biology.organism_classification, Molecular biology, Satellite virus, Clone Cells, Cell Transformation, Neoplastic, Viral replication, Avian Sarcoma Viruses, Insect Science, Satellite Viruses, embryonic structures, Clone (B-cell biology)
Abstract

Three clones of morphologically altered cells (L − MC29) of singular properties were isolated from MC29 (subgroup A) leukosis virus-infected chick embryo cells. Supernatant fluids from cultures of the cloned cells produced no transforming or interfering activity on chick embryo cells susceptible to known avian leukosis-sarcoma viruses. No virus associated with the cells was demonstrable by fluorescent-antibody staining or by electron microscopy. All L − MC29 clone cells were activated, however, by four strains of Rous-associated viruses (RAV) representative of A, B, C, and D subgroup avian leukosis viruses and by two strains of MC29 virus. Virus L − MC29 cells activated by superinfection with RAV-1 and RAV-2 was characterized by helper-dependent and helper-independent properties. These findings suggest that the strain MC29 leukosis virus, or a component thereof, possesses properties of defectiveness similar to those of the Bryan high-titer Rous sarcoma virus.

Published
1971

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