Search

Your search keyword '"Tillett, S"' showing total 2 results
Start Over Author "Tillett, S" Topic croton
2 results on '"Tillett, S"'

1. Chemical composition of the essential oil of Croton gossypiifolius from Venezuela.

Author

Suárez AI, Oropeza M, Vásquez L, Tillett S, and Compagnone RS

Subjects
Plant Leaves chemistry, Sesquiterpenes analysis, Sesquiterpenes, Germacrane analysis, Terpenes analysis, Venezuela, Croton chemistry, Oils, Volatile analysis
Abstract

The essential oil from leaves of Croton gossypiifolius Vahl. (Euphorbiaceae) was obtained by hydrodistillation, and analyzed by GC/FID and GC/MS. The constituents were identified by their mass spectra and Kovats' indices. Fifty-one compounds accounting for 92% of the oil were detected, and 47 of them were identified. The oil was dominated by oxygenated sesquiterpenes with the major presence of alpha-cedrene oxide (18.6%), spathulenol (16.3%), valencene (5.8%), geranyl-pentanoate (5.3%), alpha-cadinol (4.0%), germacrene D (3.5%) and longifolene (3.3%).

Published
2011

2. Antinociceptive and anti-inflammatory effects of Croton malambo bark aqueous extract.

Author

Suárez AI, Compagnone RS, Salazar-Bookaman MM, Tillett S, Delle Monache F, Di Giulio C, and Bruges G

Subjects
Albumins adverse effects, Analgesics, Non-Narcotic therapeutic use, Animals, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Benzoquinones adverse effects, Benzoquinones antagonists & inhibitors, Edema chemically induced, Edema drug therapy, Inflammation chemically induced, Inflammation drug therapy, Male, Medicine, Traditional, Mice, Morphine pharmacology, Morphine therapeutic use, Rats, Rats, Sprague-Dawley, Toxicity Tests, Acute, Venezuela, Analgesics, Non-Narcotic pharmacology, Anti-Inflammatory Agents, Non-Steroidal pharmacology, Croton, Nociceptors drug effects, Pain drug therapy, Phytotherapy, Plant Bark chemistry, Plant Extracts therapeutic use
Abstract

Croton malambo (K.) bark aqueous extract, popularly known in Venezuela as "palomatias" or "torco" was tested for acute toxicity and for its anti-inflammatory and antinociceptive effects using tail flick and writhing syndrome tests models, respectively. Croton malambo aqueous extract (6.15 mg/kg i.p.) administered intraperitoneally had a significant antinociceptive and anti-inflammatory effects compared to acetylsalicylic acid (200mg/kg p.o.) and sodium diclofenac (5.64 mg/kg p.o.). Studies to determine correlation between chemical composition and pharmacological activity are underway.

Published
2003
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results