This study aimed to assess subterranean termite nests in residential and open crop fields in Central Ethiopia: knowledge and perception of farmers on causes and effects. A descriptive research design was used for primary data collection from the selected district of central Ethiopia. Termite nests were counted from each kebele after clustered into local division called Gox. A total of 72 sampling frames with a 1 km2 were used for termite nests count. In addition, 190 household heads were selected at random from each kebele for questionnaires survey. Termite nests were abundant in Warabo (7.251.71 per 1000 m2), but scarce in Warke Walensu Kebele (2.250.50 per 1000 m2). Teff (49.5%) and wheat (32.6%) were the crops most severely affected by termites. The mean annual hectares of land and quintals of teff and wheat damaged per household were higher in Warabo Kebele (p = 0.000) and lowest in Warke Walensu Kebele. The annual economic loss from crops loss due to termite's effect was greater in Warabo Kebele (4722.23 ± 869.67 ETB and 4396.43 ± 852.65 ETB from teff and wheat per household, respectively). Agroecology, deforestation, grazing, and crop type were the factors that determine termite abundance and its impact on farmers' livelihoods. Mound opening and smoking were the traditional management methods used, but there was no government support. Therefore, integrated and effective termite pest management is critical for long-term food security in the study area. • Termite is the major crop pest that significantly affects the livelihood of society in the study area. • The assemblage and distribution of termites are dependent on crop type, ecology, and human activities. • The indigenous management methods used is not effective and require extensive work. [ABSTRACT FROM AUTHOR]