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1. Identification of N-Acetyldopamine Dimers from the Dung Beetle Catharsius molossus and Their COX-1 and COX-2 Inhibitory Activities

Author

Juan Lu, Qin Sun, Zheng-Chao Tu, Qing Lv, Pi-Xian Shui, and Yong-Xian Cheng

Subjects
Catharsius molossus, N-acetyldopamine dimers, COX-1, COX-2, Organic chemistry, QD241-441
Abstract

Recent studies focusing on identifying the biological agents of Catharsius molossus have led to the identification of three new N-acetyldopamine dimers molossusamide A–C (1-3) and two known compounds 4 and 5. The structures of the new compounds were identified by comprehensive spectroscopic evidences. Compound 4 was found to have inhibitory effects towards COX-1 and COX-2.

Published
2015
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