1. Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.
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Elneima, Omer, McAuley, Hamish J C, Leavy, Olivia C, Chalmers, James D, Horsley, Alex, Ho, Ling-Pei, Marks, Michael, Poinasamy, Krisnah, Raman, Betty, Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Harris, Victoria C, Houchen-Wolloff, Linzy, Saunders, Ruth M, Greening, Neil J, Richardson, Matthew, Quint, Jennifer K, Briggs, Andrew, and Docherty, Annemarie B
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VITAMIN B1 , *SARS-CoV-2 , *ERYTHROPOIETIN receptors , *FERRITIN , *MUSCLE fatigue , *COVID-19 - Abstract
The given text provides information on the Post-Hospitalisation COVID-19 (PHOSP-COVID) study, a national UK multicentre cohort study that aims to investigate the medium- and long-term effects of severe COVID-19 requiring hospitalization. The study collects data on physical measures, biological samples, and patient-reported outcome measures from participants who were hospitalized for COVID-19 and subsequently discharged. The study aims to understand the long-term health effects of COVID-19, evaluate the effects of treatments, and inform future clinical trials and care for patients with long COVID. The study has found that a significant number of participants continue to experience health impairments even 5 months after hospital discharge for COVID-19, including symptoms such as muscle aches, fatigue, impaired sleep quality, joint pain, breathlessness, and mental health issues. At 1 year after discharge, there was little improvement in symptoms and health impairments. The study has identified risk factors for lack of recovery and new or worse breathlessness. The study has strengths in its large sample size and multidimensional data collection, but there are limitations such as potential recall bias and selection bias. The data from the study can be accessed through the PHOSP-COVID study website. The study has various working groups covering different areas of research and involves multiple authors and affiliations. The research article focuses on the impact of COVID-19 on the respiratory system and the long-term effects it may have on patients. The research was conducted at the National Institute [Extracted from the article]
- Published
- 2024
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