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2 results on '"Davide Razzano"'

1. How the First Year of the COVID-19 Pandemic Impacted Patients’ Hospital Admission and Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

Author

Eugenio Martelli, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe Sangiorgi, Matilde Zamboni, Allegra R. Martelli, Giancarlo Accarino, Giuseppe Bianco, Francesco Bonanno, Umberto M. Bracale, Enrico Cappello, Giovanni Cioffi, Giovanni Colacchio, Adolfo Crinisio, Salvatore De Vivo, Carlo Patrizio Dionisi, Loris Flora, Giovanni Impedovo, Francesco Intrieri, Luca Iorio, Gabriele Maritati, Piero Modugno, Mario Monaco, Giuseppe Natalicchio, Vincenzo Palazzo, Fernando Petrosino, Francesco Pompeo, Raffaele Pulli, Davide Razzano, Maurizio R. Ruggieri, Carlo Ruotolo, Paolo Sangiuolo, Gennaro Vigliotti, Pietro Volpe, Antonella Biello, Pietro Boggia, Michelangelo Boschetti, Enrico M. Centritto, Flavia Condò, Lucia Cucciolillo, Amodio S. D’Amodio, Mario De Laurentis, Claudio Desantis, Daniela Di Lella, Giovanni Di Nardo, Angelo Disabato, Ilaria Ficarelli, Angelo Gasparre, Antonio N. Giordano, Alessandro Luongo, Mafalda Massara, Vincenzo Molinari, Andrea Padricelli, Marco Panagrosso, Anna Petrone, Serena Pisanello, Roberto Prunella, Michele Tedesco, and Alberto M. Settembrini

Subjects
COVID-19, carotid stenosis, abdominal aortic aneurysm, chronic limb-threatening ischemia, amputation, deep venous thrombosis, Medicine
Abstract

Background: To investigate the effects of the COVID-19 lockdowns on the vasculopathic population. Methods: The Divisions of Vascular Surgery of the southern Italian peninsula joined this multicenter retrospective study. Each received a 13-point questionnaire investigating the hospitalization rate of vascular patients in the first 11 months of the COVID-19 pandemic and in the preceding 11 months. Results: 27 out of 29 Centers were enrolled. April-December 2020 (7092 patients) vs. 2019 (9161 patients): post-EVAR surveillance, hospitalization for Rutherford category 3 peripheral arterial disease, and asymptomatic carotid stenosis revascularization significantly decreased (1484 (16.2%) vs. 1014 (14.3%), p = 0.0009; 1401 (15.29%) vs. 959 (13.52%), p = 0.0006; and 1558 (17.01%) vs. 934 (13.17%), p < 0.0001, respectively), while admissions for revascularization or major amputations for chronic limb-threatening ischemia and urgent revascularization for symptomatic carotid stenosis significantly increased (1204 (16.98%) vs. 1245 (13.59%), p < 0.0001; 355 (5.01%) vs. 358 (3.91%), p = 0.0007; and 153 (2.16%) vs. 140 (1.53%), p = 0.0009, respectively). Conclusions: The suspension of elective procedures during the COVID-19 pandemic caused a significant reduction in post-EVAR surveillance, and in the hospitalization of asymptomatic carotid stenosis revascularization and Rutherford 3 peripheral arterial disease. Consequentially, we observed a significant increase in admissions for urgent revascularization for symptomatic carotid stenosis, as well as for revascularization or major amputations for chronic limb-threatening ischemia.

Published
2022
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2. A cross-sectional study evaluating hospitalization rates for chronic limb-threatening ischemia during the COVID-19 outbreak in Campania, Italy

Author

Ilaria Ficarelli, Luigi Salemme, Rosario Mancusi, Eugenio Stabile, Loris Flora, Raffaele Pio Ammollo, Emilio Soreca, Daniela Viola, Paolo Sangiuolo, Enrico Cappello, Giovanni Esposito, Giovanni Cioffi, Raffaella Niola, Gennaro Vigliotti, Danilo Barbarisi, Angelo Cioppa, Umberto Bracale, Eugenio Laurenzano, Mario De Laurentis, Alfonsina M Corbisiero, Eugenio Martelli, Giancarlo Accarino, Carlo Ruotolo, Claudio Molino, Giampaolo Amabile, Gianpaolo Santini, Alessandro Luongo, Antonio D'angelo, Bruno Villari, Giuseppe Sarti, Adolfo Crinisio, Gianluca Cangiano, Pietro Landino, Claudia De Gregorio, Fernando Petrosino, Raffaele Piccolo, Davide Razzano, Michele Franzese, Stabile, E., Piccolo, R., Franzese, M., Accarino, G., Bracale, U. M., Cappello, E., Cioffi, G., Cioppa, A., Crinisio, A., Flora, L., Landino, P., Martelli, E., Mancusi, R., Niola, R., Petrosino, F., Razzano, D., Ruotolo, C., Salemme, L., Sangiuolo, P., Santini, G., Soreca, E., Vigliotti, G., Villari, B., Amabile, G., Ammollo, R. P., Barbarisi, D., Corbisiero, A. M., D'Angelo, A., Cangiano, G., De Gregorio, C., De Laurentis, M., Laurenzano, E., Ficarelli, I., Luongo, A., Molino, C., Sarti, G., Viola, D., and Esposito, G.

Subjects
medicine.medical_specialty, Cross-sectional study, medicine.medical_treatment, Ischemia, cross-sectional studies, ischemia, 030204 cardiovascular system & hematology, Rate ratio, Revascularization, COVID-19, chronic limb-threatening ischemia (CLTI), peripheral artery disease (PAD), adult, aged, aged, 80 and over, chronic disease, extremities, female, hospitalization, humans, italy, male, middle aged, peripheral arterial disease, retrospective studies, risk factors, SARS-CoV-2, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, 80 and over, 030212 general & internal medicine, Peripheral artery disease (PAD), Aged, 80 and over, business.industry, Outbreak, Original Articles, medicine.disease, Amputation, Population study, Cardiology and Cardiovascular Medicine, business
Abstract

The expansion of coronavirus disease 2019 (COVID-19) prompted measures of disease containment by the Italian government with a national lockdown on March 9, 2020. The purpose of this study is to evaluate the rate of hospitalization and mode of in-hospital treatment of patients with chronic limb-threatening ischemia (CLTI) before and during lockdown in the Campania region of Italy. The study population includes all patients with CLTI hospitalized in Campania over a 10-week period: 5 weeks before and 5 weeks during lockdown ( n = 453). Patients were treated medically and/or underwent urgent revascularization and/or major amputation of the lower extremities. Mean age was 69.2 ± 10.6 years and 27.6% of the patients were women. During hospitalization, 21.9% of patients were treated medically, 78.1% underwent revascularization, and 17.4% required amputations. In the weeks during the lockdown, a reduced rate of hospitalization for CLTI was observed compared with the weeks before lockdown (25 vs 74/100,000 inhabitants/year; incidence rate ratio: 0.34, 95% CI 0.32–0.37). This effect persisted to the end of the study period. An increased amputation rate in the weeks during lockdown was observed (29.3% vs 13.4%; p < 0.001). This study reports a reduced rate of CLTI-related hospitalization and an increased in-hospital amputation rate during lockdown in Campania. Ensuring appropriate treatment for patients with CLTI should be prioritized, even during disease containment measures due to the COVID-19 pandemic or other similar conditions.

Published
2021

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