1. Synchronization Of Autonomic Control Loops Of Blood Circulation In Patients With COVID-19
- Author
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O.M. Drapkina, Andrei I. Korolev, Ekaterina I. Borovkova, Yurii M. Ishbulatov, Alexander V. Kuligin, Alexander Yu. Gorshkov, Anatoly S. Karavaev, Viktoriia V. Skazkina, Andrei A. Fedorovich, V.A. Dadaeva, Anton R. Kiselev, and Natalia S. Krasikova
- Subjects
medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,business.industry ,General Medicine ,Phase synchronization ,Autonomic control ,Internal medicine ,Blood circulation ,Heart rate ,Synchronization (computer science) ,medicine ,Cardiology ,In patient ,Viral disease ,business - Abstract
This study aims to investigate the strength of synchronization between the autonomic control loops of the cardiovascular system (CVS) in patients with COronaVIrus Disease 2019 (COVID-19). Methods — We calculated the total percent of phase synchronization index (S index) between the loops of autonomic control of heart rate and vascular tone in two sample groups: healthy individuals and COVID-19 patients. Results — The group-average value of the S index in COVID-19 patients is lower comparing to healthy individuals, the Mann-Whitney U-test confirmed that the differences are statistically significant. Conclusion — Obtained results suggest that the decreased value of the S index reflects the presence of a viral disease, and the S index is a promising basis for non-invasive screening diagnostics of viral diseases, particularly of COVID-19.
- Published
- 2021