1. The Genetics of Human Congenital Coronary Vascular Anomalies.
- Author
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Garrido AO, Picazo B, Guadix JA, Ruiz-Villalba A, and Pérez-Pomares JM
- Subjects
- Humans, Genetic Predisposition to Disease genetics, Heart Defects, Congenital genetics, Coronary Vessel Anomalies genetics
- Abstract
The genetics of human congenital coronary vascular anomalies (hCCVA) remains largely underresearched. This is surprising, because although coronary vascular defects represent a relatively small proportion of human congenital heart disease (CHD), hCCVAs are clinically significant conditions. Indeed, hCCVA frequently associate to other congenital cardiac structural defects and may even result in sudden cardiac death in the adult. In this brief chapter, we will attempt to summarize our current knowledge on the topic, also proposing a rationale for the development of novel approaches to the genetics of hCCVA., (© 2024. The Author(s), under exclusive license to Springer Nature Switzerland AG.)
- Published
- 2024
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