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4 results on '"Van de Heyning CM"'

1. The clinical use of stress echocardiography in chronic coronary syndromes and beyond coronary artery disease: a clinical consensus statement from the European Association of Cardiovascular Imaging of the ESC.

Author

Picano E, Pierard L, Peteiro J, Djordjevic-Dikic A, Sade LE, Cortigiani L, Van De Heyning CM, Celutkiene J, Gaibazzi N, Ciampi Q, Senior R, Neskovic AN, and Henein M

Subjects
Humans, Echocardiography, Stress methods, Contrast Media, Artificial Intelligence, Echocardiography, Coronary Artery Disease diagnostic imaging
Abstract

Since the 2009 publication of the stress echocardiography expert consensus of the European Association of Echocardiography, and after the 2016 advice of the American Society of Echocardiography-European Association of Cardiovascular Imaging for applications beyond coronary artery disease, new information has become available regarding stress echo. Until recently, the assessment of regional wall motion abnormality was the only universally practiced step of stress echo. In the state-of-the-art ABCDE protocol, regional wall motion abnormality remains the main step A, but at the same time, regional perfusion using ultrasound-contrast agents may be assessed. Diastolic function and pulmonary B-lines are assessed in step B; left ventricular contractile and preload reserve with volumetric echocardiography in step C; Doppler-based coronary flow velocity reserve in the left anterior descending coronary artery in step D; and ECG-based heart rate reserve in non-imaging step E. These five biomarkers converge, conceptually and methodologically, in the ABCDE protocol allowing comprehensive risk stratification of the vulnerable patient with chronic coronary syndromes. The present document summarizes current practice guidelines recommendations and training requirements and harmonizes the clinical guidelines of the European Society of Cardiology in many diverse cardiac conditions, from chronic coronary syndromes to valvular heart disease. The continuous refinement of imaging technology and the diffusion of ultrasound-contrast agents improve image quality, feasibility, and reader accuracy in assessing wall motion and perfusion, left ventricular volumes, and coronary flow velocity. Carotid imaging detects pre-obstructive atherosclerosis and improves risk prediction similarly to coronary atherosclerosis. The revolutionary impact of artificial intelligence on echocardiographic image acquisition and analysis makes stress echo more operator-independent and objective. Stress echo has unique features of low cost, versatility, and universal availability. It does not need ionizing radiation exposure and has near-zero carbon dioxide emissions. Stress echo is a convenient and sustainable choice for functional testing within and beyond coronary artery disease., Competing Interests: Conflict of interest: None declared., (© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)

Published
2024
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2. Lifelong endurance exercise and its relation with coronary atherosclerosis.

Author

De Bosscher R, Dausin C, Claus P, Bogaert J, Dymarkowski S, Goetschalckx K, Ghekiere O, Van De Heyning CM, Van Herck P, Paelinck B, Addouli HE, La Gerche A, Herbots L, Willems R, Heidbuchel H, and Claessen G

Subjects
Humans, Male, Middle Aged, Prospective Studies, Tomography, X-Ray Computed, Computed Tomography Angiography, Oxygen, Coronary Angiography methods, Risk Factors, Coronary Artery Disease epidemiology, Coronary Artery Disease etiology, Plaque, Atherosclerotic diagnostic imaging
Abstract

Aims: The impact of long-term endurance sport participation (on top of a healthy lifestyle) on coronary atherosclerosis and acute cardiac events remains controversial., Methods and Results: The Master@Heart study is a well-balanced prospective observational cohort study. Overall, 191 lifelong master endurance athletes, 191 late-onset athletes (endurance sports initiation after 30 years of age), and 176 healthy non-athletes, all male with a low cardiovascular risk profile, were included. Peak oxygen uptake quantified fitness. The primary endpoint was the prevalence of coronary plaques (calcified, mixed, and non-calcified) on computed tomography coronary angiography. Analyses were corrected for multiple cardiovascular risk factors. The median age was 55 (50-60) years in all groups. Lifelong and late-onset athletes had higher peak oxygen uptake than non-athletes [159 (143-177) vs. 155 (138-169) vs. 122 (108-138) % predicted]. Lifelong endurance sports was associated with having ≥1 coronary plaque [odds ratio (OR) 1.86, 95% confidence interval (CI) 1.17-2.94], ≥ 1 proximal plaque (OR 1.96, 95% CI 1.24-3.11), ≥ 1 calcified plaques (OR 1.58, 95% CI 1.01-2.49), ≥ 1 calcified proximal plaque (OR 2.07, 95% CI 1.28-3.35), ≥ 1 non-calcified plaque (OR 1.95, 95% CI 1.12-3.40), ≥ 1 non-calcified proximal plaque (OR 2.80, 95% CI 1.39-5.65), and ≥1 mixed plaque (OR 1.78, 95% CI 1.06-2.99) as compared to a healthy non-athletic lifestyle., Conclusion: Lifelong endurance sport participation is not associated with a more favourable coronary plaque composition compared to a healthy lifestyle. Lifelong endurance athletes had more coronary plaques, including more non-calcified plaques in proximal segments, than fit and healthy individuals with a similarly low cardiovascular risk profile. Longitudinal research is needed to reconcile these findings with the risk of cardiovascular events at the higher end of the endurance exercise spectrum., Competing Interests: Conflict of interest: All authors declare no conflict of interest for this contribution., (© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.)

Published
2023
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3. Lifelong endurance exercise and its relation with coronary atherosclerosis

Author

De Bosscher, R, Dausin, C, Claus, P, Bogaert, J, Dymarkowski, S, Goetschalckx, K, Ghekiere, O, Van De Heyning, CM, Van Herck, P, Paelinck, B, El Addouli, H, La Gerche, A, Herbots, L, Willems, R, Heidbuchel, H, Claessen, G, Claeys, M, Hespel, P, Dresselaers, T, Miljoen, H, Belmans, A, Favere, Kasper, Vermeulen, D, Witvrouwen, I, Hansen, D, Eijnde, Bert Op't, Thijs, D, Vanvoorden, P, Van Soest, S, Master@Heart, Consortium, Master@Heart Consortium, Willems, Rik/0000-0002-5469-9609, Dausin, Christophe/0000-0001-7864-2968, Van de Heyning, Caroline/0000-0002-4661-4732, De Bosscher, Ruben, Dausin, Christophe, Claus, Piet, Bogaert, Jan, Dymarkowski, Steven, Goetschalckx, Kaatje, GHEKIERE, Olivier, van de Heyning, Caroline M., Van Herck, Paul, Paelinck, Bernard, El Addouli, Haroun, La Gerche, Andre, HERBOTS, Lieven, Willems , Rik, HEIDBUCHEL, Hein, CLAESSEN, Guido, Claeys, Mathias, Hespel, Peter, Dresselaers, Tom, Miljoen, Hielko, Belmans, Ann, Favere, Kasper, Vermeulen, Dorien, Witvrouwen, Isabel, HANSEN, Dominique, OP 'T EIJNDE, Bert, Thijs, Daisy, Vanvoorden, Peter, and Van Soest , Sofie

Subjects
Medicine and Health Sciences, Athlete's heart, Human medicine, Athlete’s heart, Cardiology and Cardiovascular Medicine, Coronary artery disease, Exercise, Computed tomography coronary angiography
Abstract

Aims The impact of long-term endurance sport participation (on top of a healthy lifestyle) on coronary atherosclerosis and acute cardiac events remains controversial. Methods and results The Master@Heart study is a well-balanced prospective observational cohort study. Overall, 191 lifelong master endurance athletes, 191 late-onset athletes (endurance sports initiation after 30 years of age), and 176 healthy non-athletes, all male with a low cardiovascular risk profile, were included. Peak oxygen uptake quantified fitness. The primary endpoint was the prevalence of coronary plaques (calcified, mixed, and non-calcified) on computed tomography coronary angiography. Analyses were corrected for multiple cardiovascular risk factors. The median age was 55 (50-60) years in all groups. Lifelong and late-onset athletes had higher peak oxygen uptake than non-athletes [159 (143-177) vs. 155 (138-169) vs. 122 (108-138) % predicted]. Lifelong endurance sports was associated with having >= 1 coronary plaque [odds ratio (OR) 1.86, 95% confidence interval (CI) 1.17-2.94], >= 1 proximal plaque (OR 1.96, 95% CI 1.24-3.11), >= 1 calcified plaques (OR 1.58, 95% CI 1.01-2.49), >= 1 calcified proximal plaque (OR 2.07, 95% CI 1.28-3.35), >= 1 non-calcified plaque (OR 1.95, 95% CI 1.12-3.40), >= 1 non-calcified proximal plaque (OR 2.80, 95% CI 1.39-5.65), and >= 1 mixed plaque (OR 1.78, 95% CI 1.06-2.99) as compared to a healthy non-athletic lifestyle. Conclusion Lifelong endurance sport participation is not associated with a more favourable coronary plaque composition compared to a healthy lifestyle. Lifelong endurance athletes had more coronary plaques, including more non-calcified plaques in proximal segments, than fit and healthy individuals with a similarly low cardiovascular risk profile. Longitudinal research is needed to reconcile these findings with the risk of cardiovascular events at the higher end of the endurance exercise spectrum. [GRAPHICS] . This study is supported by a research grant (T003717N) and R.W. is supported as a post-doctoral clinical researcher by the Fund for Scientific Research Flanders (FWO Vlaanderen), Brussels, Belgium The authors would like to thank the many staff members at the three sites for helping conduct this study. We would particularly like to thank the clinical research assistants Sofie van Soest, Dorien Vermeulen, and Daisy Thijs for their dedication and devoted efforts to include, test, and follow up participants. We would like to thank Ann Belmans for calculating the sample size and statistical advice. We would also like to thank Kris Van der Mieren (Sport- en keuringsartsen), Tom Teuglinckx (Sport- en keuringsartsen), Reynout Van Schuylenbergh (Triatlon Vlaanderen), Frank Glorieux (Cycling Vlaanderen), Paul Rowe (Sport Vlaanderen), Gert Van Goolen (Golazo), and Sven Nys (Golazo and godfather of Master@Heart) as members of the advisory committee for their insightful input on the design, the launch, and approach of the Master@Heart study.

Published
2023

4. Stress echo 2030: The novel ABCDE-(FGLPR) protocol to define the future of imaging

Author

Picano E, Ciampi Q, Cortigiani L, Arruda-Olson AM, Borguezan-Daros C, de Castro E Silva Pretto JL, Cocchia R, Bossone E, Merli E, Kane GC, Varga A, Agoston G, Scali MC, Morrone D, Simova I, Samardjieva M, Boshchenko A, Ryabova T, Vrublevsky A, Palinkas A, Palinkas ED, Sepp R, Torres MAR, Villarraga HR, Preradović TK, Citro R, Amor M, Mosto H, Salamè M, Leeson P, Mangia C, Gaibazzi N, Tuttolomondo D, Prota C, Peteiro J, Van De Heyning CM, D'Andrea A, Rigo F, Nikolic A, Ostojic M, Lowenstein J, Arbucci R, Haber DML, Merlo PM, Wierzbowska-Drabik K, Kasprzak JD, Haberka M, Camarozano AC, Ratanasit N, Mori F, D'Alfonso MG, Tassetti L, Milazzo A, Olivotto I, Marchi A, Rodriguez-Zanella H, Zagatina A, Padang R, Dekleva M, Djordievic-Dikic A, Boskovic N, Tesic M, Giga V, Beleslin B, Di Salvo G, Lorenzoni V, Cameli M, Mandoli GE, Bombardini T, Caso P, Celutkiene J, Barbieri A, Benfari G, Bartolacelli Y, Malagoli A, Bursi F, Mantovani F, Villari B, Russo A, De Nes M, Carpeggiani C, Monte I, Re F, Cotrim C, Bilardo G, Saad AK, Karuzas A, Matuliauskas D, Colonna P, Antonini-Canterin F, Pepi M, Pellikka PA, The Stress Echo Study Group Of The Italian Society Of Echocardiography And Cardiovascular Imaging Siecvi., Picano, E, Ciampi, Q, Cortigiani, L, Arruda-Olson, Am, Borguezan-Daros, C, de Castro, E Silva Pretto JL, Cocchia, R, Bossone, E, Merli, E, Kane, Gc, Varga, A, Agoston, G, Scali, Mc, Morrone, D, Simova, I, Samardjieva, M, Boshchenko, A, Ryabova, T, Vrublevsky, A, Palinkas, A, Palinkas, Ed, Sepp, R, Torres, Mar, Villarraga, Hr, Preradović, Tk, Citro, R, Amor, M, Mosto, H, Salamè, M, Leeson, P, Mangia, C, Gaibazzi, N, Tuttolomondo, D, Prota, C, Peteiro, J, Van De Heyning, Cm, D'Andrea, A, Rigo, F, Nikolic, A, Ostojic, M, Lowenstein, J, Arbucci, R, Haber, Dml, Merlo, Pm, Wierzbowska-Drabik, K, Kasprzak, Jd, Haberka, M, Camarozano, Ac, Ratanasit, N, Mori, F, D'Alfonso, Mg, Tassetti, L, Milazzo, A, Olivotto, I, Marchi, A, Rodriguez-Zanella, H, Zagatina, A, Padang, R, Dekleva, M, Djordievic-Dikic, A, Boskovic, N, Tesic, M, Giga, V, Beleslin, B, Di Salvo, G, Lorenzoni, V, Cameli, M, Mandoli, Ge, Bombardini, T, Caso, P, Celutkiene, J, Barbieri, A, Benfari, G, Bartolacelli, Y, Malagoli, A, Bursi, F, Mantovani, F, Villari, B, Russo, A, De Nes, M, Carpeggiani, C, Monte, I, Re, F, Cotrim, C, Bilardo, G, Saad, Ak, Karuzas, A, Matuliauskas, D, Colonna, P, Antonini-Canterin, F, Pepi, M, Pellikka, Pa, The Stress Echo Study Group Of The Italian Society Of Echocardiography And Cardiovascular Imaging, Siecvi., and The Stress Echo 2030 Study Group of the Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI)

Subjects
medicine.medical_specialty, Registry, Functional testing, Effectiveness, 030204 cardiovascular system & hematology, Article, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Stress Echocardiography, echocardiography, 030212 general & internal medicine, Tetralogy of Fallot, business.industry, valvular heart disease, Diastolic heart failure, Hypertrophic cardiomyopathy, COVID-19, Stress echocardiography, Sustainability, General Medicine, medicine.disease, 3. Good health, effectiveness, registry, stress echocardiography, sustainability, Coronary vasospasm, Cardiology, Medicine, Human medicine, business, effectivene
Abstract

With stress echo (SE) 2020 study, a new standard of practice in stress imaging was developed and disseminated: the ABCDE protocol for functional testing within and beyond CAD. ABCDE protocol was the fruit of SE 2020, and is the seed of SE 2030, which is articulated in 12 projects: 1-SE in coronary artery disease (SECAD), 2-SE in diastolic heart failure (SEDIA), 3-SE in hypertrophic cardiomyopathy (SEHCA), 4-SE post-chest radiotherapy and chemotherapy (SERA), 5-Artificial intelligence SE evaluation (AI-SEE), 6-Environmental stress echocardiography and air pollution (ESTER), 7-SE in repaired Tetralogy of Fallot (SETOF), 8-SE in post-COVID-19 (SECOV), 9: Recovery by stress echo of conventionally unfit donor good hearts (RESURGE), 10-SE for mitral ischemic regurgitation (SEMIR), 11-SE in valvular heart disease (SEVA), 12-SE for coronary vasospasm (SESPASM). The study aims to recruit in the next 5 years (2021–2025) ≥10,000 patients followed for ≥5 years (up to 2030) from ≥20 quality-controlled laboratories from ≥10 countries. In this COVID-19 era of sustainable health care delivery, SE2030 will provide the evidence to finally recommend SE as the optimal and versatile imaging modality for functional testing anywhere, any time, and in any patient.

Published
2021

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