Search

Metal–organic framework (MOF) materials with aqueous stability have a good potential application in the field of mimetic enzymes. However, most of them have poor robustness in aqueous solution due to competitive coordination effects between water molecules and central metal ions. Herein, a copper-based MOF (Cu-SM MOF) was prepared using copper ions and 5-(sulfomethyl) isophthalic acid (5-SMIPA) by a hydrothermal process. Considering the similarity of coordination and morphology with HKUST-1, the aqueous stability and laccase-like activity of the Cu-SM MOF were investigated using HKUST-1 as the reference. The Cu-SM MOF shows superior aqueous stability to HKUST-1 after immersion in buffer solutions, especially under alkaline conditions. Moreover, the Cu-SM MOF possesses higher catalytic activity than HKUST-1 at a high salt concentration, high temperature, etc., because the Cu-SM MOF exhibits lower Km and higher Vmax values than those of laccase and reported mimetic enzymes. The mimetic enzyme behavior of the Cu-SM MOF is demonstrated in the oxidation of phenols, as well as in the detection of 2,4-dichlorophenol (2,4-DP) and p-nitrophenol with linear ranges of 1–100 μM and 2–250 μM, and limits of detection of 0.53 μM and 1.62 μM, respectively. Owing to the excellent aqueous stability and laccase-like activity of the Cu-SM MOF, it has great application prospects in many fields, such as the determination of phenols and the treatment of industrial wastewater. [ABSTRACT FROM AUTHOR]

The morphology of nanomaterials (geometric shape and dimension) play a significant role in its various physical and chemical properties. Thus, it is essential to link morphology with performance in specific applications. For this purpose, the morphology of copper metal–organic polyhedra (Cu‐MOP) can be modulated through distinct assembly process, which facilitates the exploration of the relationship between morphology and catalytic performance. In this work, the assemblies of Cu‐MOP with three different morphologies (nanorods, nanofibers and nanosheets) were facilely prepared by the variation of solvent mixture of N, N‐dimethylformamide (DMF) and methanol, revealed the important role of the interaction between the surface group and the solvent on the morphology of these assemblies. Cu‐MOP nanofibers exhibited the highest mimetic peroxidase enzyme activity over the Cu‐MOP nanosheets and nanorods, which have been utilized in the detection of glucose. Cu‐MOPs assemblies with tunable morphology accompanied with adjustable mimic peroxidase activity, had great potential applications in the field of bioanalytical chemistry and biomedicals. [ABSTRACT FROM AUTHOR]

In this work, we designed a new fluorescent oligonucleotides-stabilized silver nanoclusters (DNA/AgNCs) probe for sensitive detection of mercury and copper ions. This probe contains two tailored DNA sequence. One is a signal probe contains a cytosine-rich sequence template for AgNCs synthesis and link sequence at both ends. The other is a guanine-rich sequence for signal enhancement and link sequence complementary to the link sequence of the signal probe. After hybridization, the fluorescence of hybridized double-strand DNA/AgNCs is 200-fold enhanced based on the fluorescence enhancement effect of DNA/AgNCs in proximity of guanine-rich DNA sequence. The double-strand DNA/AgNCs probe is brighter and stable than that of single-strand DNA/AgNCs, and more importantly, can be used as novel fluorescent probes for detecting mercury and copper ions. Mercury and copper ions in the range of 6.0–160.0 and 6–240 nM, can be linearly detected with the detection limits of 2.1 and 3.4 nM, respectively. Our results indicated that the analytical parameters of the method for mercury and copper ions detection are much better than which using a single-strand DNA/AgNCs. [ABSTRACT FROM AUTHOR]