Search

Your search keyword '"Scott, Peter J. H."' showing total 1 results
1 results on '"Scott, Peter J. H."'

1. Copper-Catalyzed [18F]Fluorination of (Mesityl)(aryl)iodoniumSalts.

Author

Ichiishi, Naoko, Brooks, Allen F., Topczewski, Joseph J., Rodnick, Melissa E., Sanford, Melanie S., and Scott, Peter J. H.

Subjects
*IODONIUM salts, *COPPER catalysts, *FLUORINATION, *MESITYLENE, *RADIOACTIVE tracers, *ARYL fluorides
Abstract

A practical, rapid, and highly regioselectiveCu-catalyzed radiofluorinationof (mesityl)(aryl)iodonium salts is described. This protocol utilizes[18F]KF to access 18F-labeled electron-rich,-neutral, and -deficient aryl fluorides under a single set of mildconditions. This methodology is applied to the synthesis of protectedversions of two important radiotracers: 4-[18F]fluorophenylalanineand 6-[18F]fluoroDOPA. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results