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Your search keyword '"F. psychrophilum"' showing total 2 results
Start Over Descriptor "F. psychrophilum" Topic copper
2 results on '"F. psychrophilum"'

1. New Copper(I) Complex with a Coumarin as Ligand with Antibacterial Activity against Flavobacterium psychrophilum .

Author

Aldabaldetrecu M, Parra M, Soto S, Arce P, Tello M, Guerrero J, and Modak B

Subjects
Animals, Cell Line, Oncorhynchus mykiss, Salmon, Anti-Bacterial Agents pharmacology, Copper pharmacology, Coumarins pharmacology, Fish Diseases microbiology, Flavobacterium drug effects
Abstract

A new copper (I) complex, [Cu(NN 1 ) 2 ](ClO 4 ) , was synthesized, where NN 1 was a imine ligand 6-((quinolin-2-ylmethylene)amino)-2H-chromen-2-one obtained by a derivatization of natural compound coumarin. The structural characterization in solution was done by NMR techniques, UV-Vis and cyclic voltammetry. The potential antibacterial effect of [Cu(NN 1 ) 2 ](ClO 4 ) , was assessed for F. psychrophilum isolated 10094. F. psychrophilum is a Gram-negative bacterium which causes diseases such as bacterial cold-water disease and rainbow trout fry syndrome, causing large economic losses in the freshwater salmonid aquaculture industry. This complex show to have antibacterial activity against F. psychrophilum 10094 at non-cytotoxic concentration in cell line derived from trout ( F. psychrophilum 10094 IC 50 16.0 ± 0.9; RT-GUT IC 50 53.0 ± 3.1 µg/mL).

Published
2020
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2. New Copper(I) Complex with a Coumarin as Ligand with Antibacterial Activity against Flavobacterium psychrophilum

Author

Juan Guerrero, Brenda Modak, Maialen Aldabaldetrecu, Sarita Soto, Mario Tello, Mick Parra, and Pablo Arce

Subjects
endocrine system, coordination compounds, Pharmaceutical Science, Flavobacterium psychrophilum, 01 natural sciences, coumarin, Flavobacterium, Article, Analytical Chemistry, Cell Line, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, copper (I), Fish Diseases, F. psychrophilum, lcsh:Organic chemistry, antibacterial activity, Coumarins, Salmon, Drug Discovery, Animals, Physical and Theoretical Chemistry, Derivatization, 030304 developmental biology, 0303 health sciences, biology, 010405 organic chemistry, Chemistry, Ligand, Organic Chemistry, biology.organism_classification, Coumarin, 0104 chemical sciences, Anti-Bacterial Agents, Trout, Chemistry (miscellaneous), Oncorhynchus mykiss, Molecular Medicine, Rainbow trout, Antibacterial activity, Bacteria, Copper, Nuclear chemistry
Abstract

A new copper (I) complex, [Cu(NN1)2](ClO4), was synthesized, where NN1 was a imine ligand 6-((quinolin-2-ylmethylene)amino)-2H-chromen-2-one obtained by a derivatization of natural compound coumarin. The structural characterization in solution was done by NMR techniques, UV-Vis and cyclic voltammetry. The potential antibacterial effect of [Cu(NN1)2](ClO4), was assessed for F. psychrophilum isolated 10094. F. psychrophilum is a Gram-negative bacterium which causes diseases such as bacterial cold-water disease and rainbow trout fry syndrome, causing large economic losses in the freshwater salmonid aquaculture industry. This complex show to have antibacterial activity against F. psychrophilum 10094 at non-cytotoxic concentration in cell line derived from trout (F. psychrophilum 10094 IC50 16.0 &plusmn, 0.9, RT-GUT IC50 53.0 &plusmn, 3.1 &micro, g/mL).

Published
2020

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