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Purpose: To evaluate the relative efficacy of peripheral defocus contact lenses (PDCLs) and orthokeratology (OK) in a real-world clinical population, and compare these results with previous randomised controlled clinical trials., Methods: Records from a university practice were reviewed to identify children who were treated with OK or PDCLs. The analysed sample contained 273 visits from 77 patients. Annualised rates of axial length (AL) progression were calculated and used as the response variable in both linear mixed-effects (LME) and nonlinear regression models., Results: On average, children were 10.7 years of age at baseline (p = 0.14 between treatments), and most patients were female. More Asian children wore OK lenses compared with PDCLs (p < 0.01). At baseline, children had ~3.00 D of myopia and 0.75 D of astigmatism in both treatment groups (p > 0.20 between treatments). LME regression models using only baseline covariates showed no evidence that the annualised change in AL differed between treatments, with or without the inclusion of age, race, sex, baseline AL or spherical equivalent refractive error. Across all possible subsets of models, age at baseline was the best predictor of annualised AL change. There was no statistical difference between parameters of an exponential decay model fitted within treatment using follow-up age as a time-varying predictor, indicating that the rate of annualised change in AL was similar for OK and PDCL., Conclusions: Retrospective analysis of real-world clinical data found no difference in annualised AL growth between PDCL and OK. Importantly, the AL progression from this clinical setting is consistent with that reported in randomised clinical trials. Therefore, continued research of real-world performance is warranted to understand the safety and efficacy of modern myopia control treatments in the broader population., (© 2023 The Authors. Ophthalmic and Physiological Optics published by John Wiley & Sons Ltd on behalf of College of Optometrists.)

Purpose: Electronic data capture is becoming increasingly common for collecting real-time patient responses. The purpose of this study was to investigate compliance with a daily electronic questionnaire regarding night-time contact lens visual performance., Method: Forty-eight subjects (34 females) were fit and dispensed two contralateral pairs of soft contact lenses (SCLs) for one week each. Subjects were sent a nightly e-mail at 8PM containing a secure, individualized link to an electronic questionnaire asking 30 questions of varying response styles (e.g., multiple choice, short answer, etc.) about SCL visual performance. Subjects were instructed to complete the questionnaire before going to bed., Results: The overall completion rate based on 676 electronic questionnaires was 95.1%. Of these, only 3.6% were completed late (<24h). The percentage of subjects completing all questionnaires was significantly higher on weekdays (96.5%; Sunday through Thursday) than on weekends (91.1%; Friday and Saturday). Fisher exact tests indicated no significant association with gender for either weekday (p=0.25) or weekend (p=0.73). Although odds ratio estimates suggested that participants 23 and older were more likely to complete the questionnaire (weekday: OR=4.39, p=0.10; weekend: OR=2.93, p=0.19), these associations did not reach statistical significance., Conclusions: E-mail based questionnaires provide an effective method for acquiring time specific responses, making them a viable clinical and research tool. The day(s) of the week on which assessments occur need to be strongly considered, as on-time compliance may be affected on weekend evenings, or possibly situations in which a typical schedule may not be followed., (Copyright © 2012 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.)

Purpose: Recent research suggests multizone/dual-focus (DF) lens corrections may aid in controlling the progression of myopia. Recently, such a soft contact lens has become commercially available in Hong Kong (MiSight, CooperVision). The purpose of the current study was to evaluate the visual acceptability of this new lens design., Methods: In a double-masked, randomized, crossover trial, 24 subjects (aged 18 to 25 years) wore MiSight contact lenses and Proclear Multifocal +2.00 diopters Add D (MF) soft contact lenses. Patient-reported outcomes (0 to 100 scale) and objective measures of visual performance were acquired for best-spectacle distance correction (BC) and with each contact lens after 1 week of daily use at HIHC (high illumination-high contrast) at distance and LILC (low illumination-low contrast) at distance, intermediate, and near., Results: There were no significant differences in HIHC distance acuity between BC and either the DF or MF lens and no difference between the DF and MF lenses. However, when measured under LILC, there were significant mean differences between each study lens and BC viewed at distance and intermediate. The LILC logMAR visual acuity was not significantly different between the DF and MF lenses at any viewing distance. Although average visual quality and ghosting ratings for both DF and MF study lenses were significantly lower than habitual under all conditions, there were no significant differences between the DF and MF lenses (p = 0.448)., Conclusions: Good acuity, similar to that attainable with typical MF lens correction, is attainable with a new contact lens designed to control myopia progression. However, like other contact lenses that contain multiple refractive zones, some decrease in visual performance may be experienced.