1. Patch test results with the European baseline series, 2019/20—Joint European results of the ESSCA and the EBS working groups of the ESCD, and the GEIDAC.
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Uter, Wolfgang, Wilkinson, S. Mark, Aerts, Olivier, Bauer, Andrea, Borrego, Leopoldo, Brans, Richard, Buhl, Timo, Dickel, Heinrich, Dugonik, Aleksandra, Filon, Francesca Larese, Garcìa, Pedro Mercader, Giménez‐Arnau, Ana, Patruno, Cataldo, Pesonen, Maria, Pónyai, Györgyi, Rustemeyer, Thomas, Schubert, Steffen, Schuttelaar, Marie‐L. A., Simon, Dagmar, and Stingeni, Luca
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ALLERGENS , *PROPOLIS , *CONFIDENCE intervals , *METHACRYLATES - Abstract
Background: Continual analyses of patch test results with the European baseline series (EBS) serve both contact allergy surveillance and auditing the value of included allergens. Objectives: To present results of current EBS patch testing, obtained in 53 departments in 13 European countries during 2019 and 2020. Methods: Anonymised or pseudonymised individual data and partly aggregated data on demographic/clinical characteristics and patch test rest results with the EBS were prospectively collected and centrally pooled and analysed. Results: In 2019 and 2020, 22 581 patients were patch tested with the EBS. Sensitization to nickel remained most common (19.8 [19.2–20.4]% positivity [95% confidence interval]). Fragrance mix I and Myroxylon pereirae yielded very similar results with 6.80 (6.43–7.19)% and 6.62 (6.25–7.00)% positivity, respectively. Formaldehyde at 2% aq. yielded almost one percentage point more positive reactions than 1% concentration (2.49 [2.16–2.85]% vs. 1.59 [1.33–1.88]); methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and MI alone up to around 5% positives. Among the new additions, propolis was most commonly positive (3.48 [3.16–3.82]%), followed by 2‐hydroxyethyl methacrylate (2.32 [2.0–2.68]%). Conclusion: Ongoing surveillance on the prevalence of contact sensitization contributes to an up‐to‐date baseline series containing the most frequent and/or relevant contact sensitizers for routine patch testing in Europe. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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