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Forests are important ecosystems offering extensive material and immaterial benefits to people and the environment. If not well monitored and sustainably managed, forest resource use can lead to degradation, which has global environmental and socio-economic implications. There is currently limited information on the factors that lead to forest use in the Cryptosepalum forests of Zambia, and how these factors potentially influence forest integrity. This study aimed at establishing the socio-economic aspects that determine resource utilisation and forest loss in the Cryptosepalum forest of Manyinga and Zambezi Districts of North-western Zambia. Using a semi-structured questionnaire 207 randomly selected households were interviewed in 7 villages surrounding the Cryptosepalum forest (4 in Manyinga and 3 in Zambezi district). Additionally, three focus Group Discussions were conducted to triangulate interview data. Descriptive statistics, Pearson's Chi-square test of independence and binary logistic regression were used to analyse the data. The study established 14 forest products used by local communities in the study sites. Socio-economic factors, namely; gender, level of education, household size, wealth, and residence status significantly influenced use of 9 of the 14 forest products. Further, significant relationships (p