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© 2018 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 license: http://creativecommons.org/licenses/by-nc-nd/4.0/ This author accepted manuscript is made available following 24 month embargo from date of publication (April 2018) in accordance with the publisher’s archiving policy, This paper presents the design and development of a smartphone-based urinalysis device that has the ability for chronic kidney disease (CKD) patients themselves to conduct rapid and reliable quantitative urinalysis of human serum albumin (HSA) using an aggregation-induced emission (AIE) nanomaterial bioprobe with their own smartphones. The focus of this paper is a novel solution to the device agnosticism issue as a wide diversity of smartphones co-exist in the market. The solution comprises: a) custom-design and fabrication of an imaging housing that provides a consistent imaging condition regardless of the physical dimensions and the camera position of the smartphone used, b) orchestration of an image processing and analysis process that produces consistent image colour intensity values regardless of the camera sensor and imaging software used by the smartphone, and c) special design and development of an intuitive cross-platform mobile application that is scalable to growth, adaptable to changes, resilient to loss of data, and has an extremely low requirement for smartphone hardware. Preliminary evaluation of the device has confirmed the effectiveness of the proposed solution and the viability of such a smartphone-based device for people who have already developed or are prone to CKD to regularly perform point-of-care (POC) urine testing in order to self monitor their own health conditions without the burden of frequent visits to their doctors.

The National Serology Reference Laboratory, Australia (NRL) has quality assured the serology for high risk blood-borne infections since 1985, commencing with anti-Human Immunodeficiency Virus (HIV) enzyme immunoassays and later extending the programmes to other blood-borne virus testing and to nucleic acid testing. A quality control (QC) programme was considered the most appropriate manner in which to achieve real-time monitoring. An Internet-based application, EDCNet, facilitates the entry of results of QC sample testing and returns the analysed results instantaneously. Results can be displayed in a variety of tables and charts, so that QC results from blood service and diagnostic laboratories can be monitored. Comparison of results between laboratories using the same system offers monitoring of accuracy, while within-laboratory comparisons offer monitoring of the assay precision. More than 200,000 data points were submitted to EDCNet in 2002 from blood service laboratories as well as from diagnostic laboratories. Analysis of reagent batch variability was determined, e.g. the coefficient of variation between batches of seven assays used to detect anti-hepatitis C virus (HCV) antibodies ranged from 4.9% to 21.6%. Using EDCNet, laboratories can monitor both precision and accuracy of results by comparison with the results of other laboratories. The system may be a highly cost-effective method for maintaining quality.

Effective designs rarely emerge from good structural design or aesthetics alone. It is more often the result of the end product's overall design integrity. Added to this, design is inherently an interdisciplinary collaborative activity. With this in mind, today's tools are not powerful enough to design complex physical environments, such as command control centers or hospital operating theaters. This paper presents the concept of employing projector-based augmented reality techniques to enhance interdisciplinary design processes. Refereed/Peer-reviewed

Effective designs rarely emerge from good structural design or aesthetics alone. It is more often the result of the end product's overall design integrity. Added to this, design is inherently an interdisciplinary collaborative activity. With this in mind, today's tools are not powerful enough to design complex physical environments, such as command control centers or hospital operating theaters. In this demo a process for designing small appliances using spatial augmented reality is presented. The goal of this demo is to show how using a SAR environment can improve the design process. Refereed/Peer-reviewed