Women worldwide are afflicted by breast cancer, a widely occuring health issue that causes a large number of deaths. This paper aims to review and present several approaches to identify breast cancers using ML algorithms and Biosensors. The objective is to investigate the application of multiple algorithms based on Machine Learning approach and biosensors for early breast cancer detection. Biosensors and machine learning are needed to identify cancers based on microscopic images, that is why automation is needed. ML aims to make computers capable of self-learning. Rather than relying on explicit pre-programmed rules and models, it is based on identifying patterns in observed data and building models to predict outcomes. We have compared and analyzed various types of algorithms like fuzzy ELM-RBF, SVM, SVR, RVM, Naive Bayes, K-NN, DT, ANN, BPNN and Random forest over varieties of databases like images digitized from fine needle aspirations (FNAs) of breast masses, Scanned film mammography, Breast infrared images, MR Images, Data collected by using the blood analyses, and Histopathology image samples. The result is compared on performance metric elements like accuracy, precision and recall. Further, we have used Biosensors to determine the presence of a specific biological analyte by transforming the cellular constituents of proteins, DNA, or RNA into electrical signals that can be detected and analyzed. Here, we have compared detection of different types of analyte like HER2, miRNA 21, miRNA 155, MCF-7 cells, DNA, BRCA1, BRCA2, human tears and saliva using different types of biosensors like FET, Electrochemical, Sandwich electrochemical, etc. Several biosensors use a different type of specification which is also discussed. The result of which is analysed on the basis of detection limit, linear ranges and response time. Different studies and related articles were ultimately reviewed and analyzed systematically and the ones published from 2010 to 2021 were considered. Biosensors and machine learning both have the potential to detect breast cancer in a fast and effective way.