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In this study, the relationship between the brain parenchymal density, the cerebral vessel density, the mean corpuscular hemoglobin (MCH) content, the mean corpuscular hemoglobin concentration (MCHC), and the morbidity associated with lacunar infarction of residents living in either the plains or the plateau regions were analyzed and compared for their potential clinical implications. Clinical data from the brain CT scans of individuals living in either the plain or plateau regions (129 each) were collected. Specifically, the CT values for basal ganglia, the middle cerebral artery, and the superior sagittal sinus, along with the number of patients with lacunar infarction, were collected. In addition, the MCH and MCHC values were measured in blood samples collected within 48 h following the CT scans. For statistical analysis, an independent sample t-test, Pearson's correlation test (permutation test), and Chi-squared test were employed. The inhabitants of the plateau had a significantly higher CT value of basal ganglia, the middle cerebral artery, and superior sagittal sinus and also higher levels of MCH and MCHC in the blood (ps < 0.001) than the inhabitants of the plains region. Further, there was a significant positive correlation between the three aforementioned CT values and the MCH and MCHC findings. However, no significant differences were found in the morbidity of lacunar infarction between these two regions (p > 0.05). The inhabitants in the plateau have a significantly higher brain parenchymal density, higher CT value for cerebral vessels density, and higher blood MCH and MCHC levels in comparison with individuals occupying the plains. Concurrently, the parenchymal density and the CT values are shown to be positively correlated with the MCH and MCHC content in the blood. [ABSTRACT FROM AUTHOR]

The present study aimed to apply the best single-energy (SE) scanning in energy spectrum computed tomography (CT) to evaluate the usefulness of lower extremity arterial angiography imaging in patients with lower extremity arterial occlusive disease. A total of 64 patients diagnosed with lower extremity arterial occlusive disease were randomly selected and divided into either the experimental group (n=32) or the control group (n=32). The two treatment groups were scanned for lower extremity arteriography using the best SE scanning mode of energy spectrum CT Gemstone imaging (GSI) and mixed energy scanning mode of multi-slice helical CT (MSCT). The CT images, image noise, contrast-to-noise ratio (CNR) and quality scores of the images of lower extremity arteries between the two groups were compared. Image quality of the two experimental groups were independently evaluated by two imaging diagnostic physicians. The CT scores and CNR of the lower extremity arteries were significantly higher in the experimental group compared with the control group (P<0.01). No statistically significant differences in the background noise between the two groups were observed (P<0.05). The image quality scores of two groups, with the differences between the two diagnosticians, were found to be statistically significant (P<0.01). In the lower extremity arterial angiography, the image quality of the best SE in the CT GSI scanning mode was observed to be superior to that taken using MSCT mixed energy scanning mode. [ABSTRACT FROM AUTHOR]