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Your search keyword '"Izzo, Andrea"' showing total 3 results
Start Over Author "Izzo, Andrea" Topic computed tomography
3 results on '"Izzo, Andrea"'

1. Computed tomography densitometric study of anti-angiogenic effect of regorafenib in colorectal cancer liver metastasis.

Author

Reginelli, Alfonso, Clemente, Alfredo, Cardone, Claudia, Urraro, Fabrizio, Izzo, Andrea, Martinelli, Erika, Troiani, Teresa, Ciardiello, Fortunato, Brunese, Luca, and Cappabianca, Salvatore

Subjects
ANTHROPOMETRY, COLON tumors, COMPUTED tomography, DIGITAL image processing, LIVER tumors, NEOVASCULARIZATION inhibitors, PYRIDINE, RECTUM tumors, TREATMENT effectiveness, UREA, THERAPEUTICS
Abstract

Aim: Regorafenib induces radiological changes in liver metastasis among patients with metastatic colorectal cancer (mCRC). The standard criteria used to evaluate solid tumor response (Response Evaluation Criteria in Solid Tumors) may be limited in assessing response to biologic agents with anti-angiogenic action.Patients& Methods: A total of 67 hepatic lesions in 32 selected patients were analyzed to evaluate tumor attenuation as measured by Hounsfield unit (HU) and size changes.Results: Following two cycles of regorafenib, tumor HU values decreased in the in 73.1% (49/67) of lesions (average HU changes -25.6%) while tumor size increased in 64.2% (43/67) of them (average size changes +25.4%).Conclusion: The computed tomography density changes evaluation may be an additional tool, in combination with tumor sizing, to evaluate tumor response in patients treated with regorafenib. [ABSTRACT FROM AUTHOR]

Published
2018
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2. Sphenoidal pneumosinus dilatans due to anterior skull base meningiomas – CT and MRI aspects: Report of two new cases and literature review.

Author

Scuotto, Assunta, Saracino, Dario, Rotondo, Michele, Izzo, Andrea, Urraro, Fabrizio, Cappabianca, Salvatore, and Sampaolo, Simone

Abstract

We report on two patients disclosing a pneumosinus dilatans (PSD) and an anterior skull base meningioma. Our findings, together with those from the pertinent literature, support the thought that this infrequent anomaly of paranasal sinuses is a useful clue to suspect a concomitant meningioma. Moreover, hypotheses concerning the pathophysiology of PSD are discussed. [ABSTRACT FROM AUTHOR]

Published
2016
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3. Computed tomography densitometric study of anti-angiogenic effect of regorafenib in colorectal cancer liver metastasis

Author

Teresa Troiani, Salvatore Cappabianca, Andrea Izzo, Alfonso Reginelli, Fortunato Ciardiello, Fabrizio Urraro, Erika Martinelli, Luca Brunese, Alfredo Clemente, Claudia Cardone, Reginelli, Alfonso, Clemente, Alfredo, Cardone, Claudia, Urraro, Fabrizio, Izzo, Andrea, Martinelli, Erika, Troiani, Teresa, Ciardiello, Fortunato, Brunese, Luca, and Cappabianca, Salvatore

Subjects
Male, density reduction, Cancer Research, Pyridines, Colorectal cancer, Angiogenesis Inhibitors, Computed tomography, Tumor response, 030218 nuclear medicine & medical imaging, Metastasis, chemistry.chemical_compound, 0302 clinical medicine, CRC liver metastases, RECIST 1.1, anti-angiogenic effect, colorectal cancer, computed tomography, oncologic imaging, regorafenib, tumor response, CRC liver metastase, Image Processing, Computer-Assisted, medicine.diagnostic_test, Liver Neoplasms, General Medicine, Middle Aged, Tumor Burden, Treatment Outcome, Oncology, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, Adult, medicine.medical_specialty, Urology, 03 medical and health sciences, Hounsfield scale, Regorafenib, medicine, Humans, Aged, business.industry, Phenylurea Compounds, Anti angiogenic, medicine.disease, chemistry, sense organs, Tomography, X-Ray Computed, business
Abstract

Aim: Regorafenib induces radiological changes in liver metastasis among patients with metastatic colorectal cancer (mCRC). The standard criteria used to evaluate solid tumor response (Response Evaluation Criteria in Solid Tumors) may be limited in assessing response to biologic agents with anti-angiogenic action. Patients & methods: A total of 67 hepatic lesions in 32 selected patients were analyzed to evaluate tumor attenuation as measured by Hounsfield unit (HU) and size changes. Results: Following two cycles of regorafenib, tumor HU values decreased in the in 73.1% (49/67) of lesions (average HU changes -25.6%) while tumor size increased in 64.2% (43/67) of them (average size changes +25.4%). Conclusion: The computed tomography density changes evaluation may be an additional tool, in combination with tumor sizing, to evaluate tumor response in patients treated with regorafenib.

Published
2018

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