4 results on '"Lord, Elizabeth L"'
Search Results
2. Trends associated with distal biceps tendon repair in the United States, 2007 to 2011.
- Author
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Wang, Dean, Joshi, Nirav B., Petrigliano, Frank A., Cohen, Jeremiah R., Lord, Elizabeth L., Wang, Jeffrey C., and Jones, Kristofer J.
- Abstract
Background Current studies investigating surgical treatment of distal biceps tendon tears largely consist of small, retrospective case series. The purpose of this study was to investigate the current patient demographics, surgical trends, and postoperative complication rates associated with operative treatment of distal biceps tendon tears using a large database of privately insured, non-Medicare patients. Methods Patients who underwent surgical intervention for distal biceps tendon tears from 2007 to 2011 were identified using the PearlDiver database. Demographic and surgical data as well as postoperative complications were reviewed. Statistical analysis was performed using linear regression analysis and χ 2 tests, with statistical significance set at P < .05. Results A total of 1443 patients underwent surgical treatment for distal biceps tendon tears. Men and patients aged 40 to 59 years accounted for 98% and 72% of the cohort, respectively. Regarding surgical technique, reinsertion to the radial tuberosity was preferred (95%) over tenodesis to the brachialis (5%) ( P < .01). In total, revision surgery for tendon rerupture occurred in 5.4% of treated patients. The incidence of revision surgery for rerupture in acute and chronic distal biceps tears was 5.1% and 7.0%, respectively ( P = .36). Postoperative infection and peripheral nerve injury rates were 1.1% and 0.6%, respectively. Conclusion Surgeons strongly preferred anatomic reinsertion to the radial tuberosity for treatment, regardless of the chronicity of the injury. Postoperative complication rates were similar to those found in prior studies, although the true rate of rerupture may be higher than previously thought. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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- View/download PDF
3. Prediction of Major Complications and Readmission After Lumbar Spinal Fusion: A Machine Learning–Driven Approach.
- Author
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Shah, Akash A., Devana, Sai K., Lee, Changhee, Bugarin, Amador, Lord, Elizabeth L., Shamie, Arya N., Park, Don Y., van der Schaar, Mihaela, and SooHoo, Nelson F.
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SPINAL fusion , *PATIENT readmissions , *WORKERS' compensation , *RECEIVER operating characteristic curves , *BRAIN concussion , *MACHINE learning , *ANGINA pectoris - Abstract
Given the significant cost and morbidity of patients undergoing lumbar fusion, accurate preoperative risk-stratification would be of great utility. We aim to develop a machine learning model for prediction of major complications and readmission after lumbar fusion. We also aim to identify the factors most important to performance of each tested model. We identified 38,788 adult patients who underwent lumbar fusion at any California hospital between 2015 and 2017. The primary outcome was major perioperative complication or readmission within 30 days. We build logistic regression and advanced machine learning models: XGBoost, AdaBoost, Gradient Boosting, and Random Forest. Discrimination and calibration were assessed using area under the receiver operating characteristic curve and Brier score, respectively. There were 4470 major complications (11.5%). The XGBoost algorithm demonstrates the highest discrimination of the machine learning models, outperforming regression. The variables most important to XGBoost performance include angina pectoris, metastatic cancer, teaching hospital status, history of concussion, comorbidity burden, and workers' compensation insurance. Teaching hospital status and concussion history were not found to be important for regression. We report a machine learning algorithm for prediction of major complications and readmission after lumbar fusion that outperforms logistic regression. Notably, the predictors most important for XGBoost differed from those for regression. The superior performance of XGBoost may be due to the ability of advanced machine learning methods to capture relationships between variables that regression is unable to detect. This tool may identify and address potentially modifiable risk factors, helping risk-stratify patients and decrease complication rates. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
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4. Surgical treatment of metastatic spine disease: an update on national trends and clinical outcomes from 2010 to 2014.
- Author
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Hsiue, Peter P., Kelley, Benjamin V., Chen, Clark J., Stavrakis, Alexandra I., Lord, Elizabeth L., Shamie, Arya N., Hornicek, Francis J., and Park, Don Y.
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SPINE diseases , *SURGICAL site infections , *NURSING care facilities , *PATIENT readmissions , *SPINAL surgery - Abstract
Background Context: Metastatic spine disease (MSD) is becoming more prevalent as medical treatment for cancers advance and extend survival. More MSD patients are treated surgically to maintain neurological function, ambulation, and quality of life.Purpose: The purpose of this study was to use a large, nationally representative database to examine the trends, patient outcomes, and health-care resource utilization associated with surgical treatment of MSD.Design: This was an epidemiologic study using national administrative data from the Nationwide Readmissions Database (NRD).Patient Sample: All patients in the NRD from 2010 to 2014 who underwent spinal surgery were included in the study.Outcome Measures: Mortality, blood transfusion, complications, length of stay, cost, and discharge location during index hospitalization as well as hospital readmission and revision surgery within 90-days of surgery were analyzed.Methods: International Classification of Diseases, Ninth Revision, (ICD-9) codes was used to identify patients of interest within the NRD from 2010 to 2014. Patients were separated into two cohorts - those with MSD and those without. Trends for surgical treatment of MSD were assessed and outcomes measures for both cohorts were analyzed and compared.Results: The number of surgical treatments for MSD increased from 6,007 in 2010 to 7,032 in 2014 (p-trend<.0001) which represented a 17.1% increase. During index hospitalization, MSD patients had an increased risk of mortality (odds ratio [OR]=3.22, 95% confidence interval [CI]: 2.85-3.63, p<.0001), blood transfusion (OR=2.93, 95% CI: 2.66-3.23, p<.0001), any complication (OR=1.24, 95% CI: 1.18-1.31, p<.0001), and discharge to skilled nursing facility (OR=1.51, 95% CI:1.41-1.61, p<.0001). MSD patients had longer average length of stay (13.05 vs. 4.56 days, p<.0001) and cost ($49,421.75 vs. $26,190.37, p<.0001) during index hospitalization. Furthermore, MSD patients had an increased risk of hospital readmission (OR=2.82, 95% CI: 2.68-2.96, p<.0001), readmission for surgical site infection (OR=2.38, 95% CI: 2.20-2.58, p<.0001), and readmission with neurologic deficits (OR=1.62, 95% CI: 1.27-2.06, p<.0001) despite a decreased risk of revision fusion (OR=0.71, 95% CI: 0.53-0.96, p=.026).Conclusions: The number of MSD patients who undergo surgical treatments is increasing. Not only do these patients have worse outcomes during index hospitalization, but they are also at an increased risk of hospital readmission for surgical site infection and neurologic complications. These findings stress the need for multidisciplinary perioperative treatment plans that mitigate risks and facilitate quick, effective recovery in these unique, at-risk patients. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
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