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Background: Poor glycaemic control of diabetes is often associated with micro- and macro-vascular complications and surprisingly, the prevalence of poor glycaemic control is getting higher in Malaysia. It remains a public health challenge in managing patients with diabetes. Hence, this study aimed to determine the clinical parameters that are associated with poor glycaemic control to help medical practitioner to anticipate these factors in treating patient with diabetes particularly those with poor glycaemic control. Materials and Methods: A comparative cross-sectional study between groups of good glycaemic control and poor glycaemic control patients was conducted among type 2 diabetic patients who fulfilled study criteria in Pasir Puteh district, Kelantan. Eligible samples registered in the National Diabetes Registry from 1st January 2019 until 31st December 2019 were recruited into the study. Descriptive statistics, simple and multiple logistic regressions were used for data analysis. Result: As of 31st December 2019, there were 5339 diabetic patients from Pasir Puteh district registered in the National Diabetes Registry. Multivariable analysis revealed duration of diabetes, systolic blood pressure, triglycerides and low-density lipoproteins level as the significant clinical factors associated with poor glycaemic control with adjusted odds ratio (AOR) of 1.08 (95%CI: 1.04, 1.12; p<0.001), AOR 1.02 (95%CI: 1.01, 1.03; p=0.002), AOR 1.60 (95%CI: 1.30, 1.94; p<0.001) and AOR 1.47 (95%CI: 1.29, 1.69; p<0.001), respectively. Conclusion: In conclusion, glycaemic control is largely influenced by modifiable risk factors. Managements focusing on these modifiable risk factors will help clinicians to sustain optimize glycaemic control in T2DM patients. [ABSTRACT FROM AUTHOR]