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Coordination of international aphasia research would minimise duplication of effort, support synergistic international activities across languages and multidisciplinary perspectives, and promote high-quality conduct and reporting of aphasia research, thereby increasing the relevance, transparency, and implementation of findings. The Collaboration of Aphasia Trialists (CATs) sought to develop an aphasia research agenda to direct future research activities, based on priorities shared by people with aphasia, family members, and healthcare professionals. Our established international research network spanning 33 countries contributed to this activity. Research literature reporting the priorities of stakeholders was reviewed and synthesized (phase 1). Representatives from Working Groups on Aphasia Assessment & Outcomes, Prognosis & Predictors of Recovery, Effectiveness of Interventions, and Societal Impact & Reintegration participated in a two-day research agenda-setting meeting. The CATs expert panel refined research objectives and identified constituent components of research and methodological developments required to address these research components. The objectives and research components were grouped into overarching themes (phase 2). The resultant list was then circulated to more than 180 CATs members for review, revision, and approval. Consensus on the final aphasia research agenda and roadmap was reached by CATs executive committee (phase 3). The expert panel identified five overarching research themes: (i) evidence-based interventions for people with aphasia, (ii) effective interventions to support those communicating with people with aphasia, (iii) cross-linguistic assessment and core outcomes for aphasia research, (iv) predictors of language recovery, and (v) clinical implementation of research findings. Within these broad themes, 30 research objectives and 91 individual aphasia research components were identified and sequentially ordered. This agenda builds on research priorities identified by people with aphasia and their families, and includes priorities of healthcare professionals and researchers, and will support the rehabilitation and recovery of people with aphasia. Our internationally relevant research agenda promotes rigor in methodology, considers international applicability, synergistic activities, and sharing of resources and expertise. [ABSTRACT FROM AUTHOR]

Background: Comprehension of reversible sentences that have derived word order has often been reported as impaired in agrammatic aphasia. Most accounts of this phenomenon refer to the syntactic differences between derived and base word order of the arguments. However, it has been demonstrated that in agrammatic spontaneous speech in standard Indonesian (SI) passives are produced at a rate that is proportional to that of healthy speakers. The main difference between passives in SI and in other languages is the frequency with which passives are used: passives in SI are highly frequent. The high frequency can be explained by the fact that passives are used for politeness reasons, saliency of the passive morphology, earlier acquisition, and formal simplicity of the passive structure. Aims: The purpose of the current study is to investigate comprehension of the passive as a derived structure in SI and the influence of frequency. Methods & Procedures: A sentence-to-picture matching task was developed to test four reversible sentence types (active, passive, subject cleft and object cleft). There are three variables that are of interest, that is, word order, embedding and relative frequency of structures. Eleven agrammatic speakers classified as suffering from Broca’s aphasia were tested. Outcomes & Results: The passive sentences were comprehended equally well as the active sentences. Embedding had limited effects: subject clefts were understood as well as actives and passives. Object clefts, however, were understood poorly and significantly worse than the three other sentence types. Conclusions: The sentence comprehension deficit pattern shown in SI individuals with Broca’s aphasia introduces frequency of a syntactic structure as an additional factor to consider. Whether frequency or pragmatic constraints protects against erosion of the passive in Broca’s aphasia in SI remains an open question. [ABSTRACT FROM AUTHOR]