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2. A systematic review and meta-analysis of surgery delays and survival in breast, lung and colon cancers: Implication for surgical triage during the COVID-19 pandemic.

Author

Johnson BA, Waddimba AC, Ogola GO, Fleshman JW Jr, and Preskitt JT

Subjects
Breast Neoplasms diagnosis, Breast Neoplasms mortality, COVID-19 epidemiology, Colonic Neoplasms diagnosis, Colonic Neoplasms mortality, Communicable Disease Control standards, Disease-Free Survival, Female, Humans, Lung Neoplasms diagnosis, Lung Neoplasms mortality, Medical Oncology standards, Medical Oncology statistics & numerical data, Medical Oncology trends, Mortality trends, Neoplasm Staging, Pandemics prevention & control, Practice Guidelines as Topic, Time Factors, Time-to-Treatment standards, Time-to-Treatment statistics & numerical data, Time-to-Treatment trends, Triage standards, Triage trends, Breast Neoplasms surgery, COVID-19 prevention & control, Colonic Neoplasms surgery, Lung Neoplasms surgery, Triage statistics & numerical data
Abstract

Background: Thousands of cancer surgeries were delayed during the peak of the COVID-19 pandemic. This study examines if surgical delays impact survival for breast, lung and colon cancers., Methods: PubMed/MEDLINE, EMBASE, Cochrane Library and Web of Science were searched. Articles evaluating the relationship between delays in surgery and overall survival (OS), disease-free survival (DFS) or cancer-specific survival (CSS) were included., Results: Of the 14,422 articles screened, 25 were included in the review and 18 (totaling 2,533,355 patients) were pooled for meta-analyses. Delaying surgery for 12 weeks may decrease OS in breast (HR 1.46, 95%CI 1.28-1.65), lung (HR 1.04, 95%CI 1.02-1.06) and colon (HR 1.24, 95%CI 1.12-1.38) cancers. When breast cancers were analyzed by stage, OS was decreased in stages I (HR 1.27, 95%CI 1.16-1.40) and II (HR 1.13, 95%CI 1.02-1.24) but not in stage III (HR 1.20, 95%CI 0.94-1.53)., Conclusion: Delaying breast, lung and colon cancer surgeries during the COVID-19 pandemic may decrease survival., (Copyright © 2020 Elsevier Inc. All rights reserved.)

Published
2021
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3. Colon cancer.

Author

Benson AB 3rd, Arnoletti JP, Bekaii-Saab T, Chan E, Chen YJ, Choti MA, Cooper HS, Dilawari RA, Engstrom PF, Enzinger PC, Fleshman JW Jr, Fuchs CS, Grem JL, Knol JA, Leong LA, Lin E, May KS, Mulcahy MF, Murphy K, Rohren E, Ryan DP, Saltz L, Sharma S, Shibata D, Skibber JM, Small W Jr, Sofocleous CT, Venook AP, and Willett C

Subjects
Algorithms, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Carcinoma diagnosis, Carcinoma etiology, Carcinoma pathology, Colonic Neoplasms diagnosis, Colonic Neoplasms etiology, Colonic Neoplasms pathology, Combined Modality Therapy, Continuity of Patient Care, Digestive System Surgical Procedures statistics & numerical data, Humans, Maintenance Chemotherapy methods, Maintenance Chemotherapy statistics & numerical data, Medical Oncology legislation & jurisprudence, Medical Oncology standards, Neoadjuvant Therapy, Neoplasm Metastasis, Radiotherapy statistics & numerical data, Recurrence, Carcinoma therapy, Colonic Neoplasms therapy, Practice Guidelines as Topic
Published
2011
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4. Learning to recycle.

Author

Fleshman JW Jr

Subjects
Female, Humans, Male, Colectomy adverse effects, Colonic Neoplasms surgery, Diverticulum, Colon surgery
Published
2011
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